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Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01760018
First Posted: January 3, 2013
Last Update Posted: February 19, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Yonsei University
  Purpose
Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire.

Condition Intervention
Thyroid Operation Under General Anesthesia Drug: desflurane group Drug: TIVA group

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)

Resource links provided by NLM:


Further study details as provided by Yonsei University:

Primary Outcome Measures:
  • QoR-40 score [ Time Frame: at 24 hours later after surgery ]
    QoR-40 score is going to be measured at preoperative period, 24 hours, and 48 hours later after surgery.


Enrollment: 76
Study Start Date: December 2012
Study Completion Date: January 2013
Primary Completion Date: January 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Desflurane group Drug: desflurane group
anesthesia is maintained with desflurane and remifentanil (Desflurane group)
Active Comparator: TIVA(total intravenous anesthesia) group Drug: TIVA group
anesthesia is maintained with fresofol and remifentanil (TIVA group).

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • patients who are undergoing thyroid operation belong to ASA class 1 or 2

Exclusion Criteria:

  • patients who are belongs to ASA class 3 or more,
  • patients who have underlying complicated cardiovascular or psychological disease.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01760018


Locations
Korea, Republic of
Severance Hospital
Seoul, Korea, Republic of, 120-752
Sponsors and Collaborators
Yonsei University
  More Information

Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Yonsei University
ClinicalTrials.gov Identifier: NCT01760018     History of Changes
Other Study ID Numbers: 4-2012-0748
First Submitted: December 31, 2012
First Posted: January 3, 2013
Last Update Posted: February 19, 2014
Last Verified: February 2014

Keywords provided by Yonsei University:
desflurane, total intravenous anesthesia, QoR-40

Additional relevant MeSH terms:
Anesthetics
Remifentanil
Desflurane
Isoflurane
Central Nervous System Depressants
Physiological Effects of Drugs
Analgesics, Opioid
Narcotics
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Hypnotics and Sedatives
Anesthetics, Intravenous
Anesthetics, General
Anesthetics, Inhalation