DIT After RYGB - A Prospective Study (DIT RYGB)
|ClinicalTrials.gov Identifier: NCT01759667|
Recruitment Status : Completed
First Posted : January 3, 2013
Last Update Posted : January 3, 2013
|Condition or disease||Intervention/treatment||Phase|
|Obesity Morbid Obesity Bariatric Surgery||Other: A standard mixed Meal||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||13 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Diet-induced Thermogenesis After Roux-en-Y Gastric Bypass - A Prospective Study|
|Study Start Date :||August 2012|
|Actual Primary Completion Date :||October 2012|
|Actual Study Completion Date :||October 2012|
Experimental: A standard mixed Meal
The standard mixed meal was composed of a chicken salad sandwich and 200ml of coconut water, totalling 260 kcal, distributed among carbohydrates (62%), proteins (12%) and lipids (26%).
Other: A standard mixed Meal
All patients underwent an indirect calorimetry test, after a 12-h period of fasting from food and water, avoiding intake of alcohol or coffee, and avoiding physical exercise and cigarettes the day before the examination. To examine possible changes in the thermogenic effect of food, patients received a standard mixed meal (200 ml coconut water and a chicken salad sandwich using whole wheat bread). They then repeated the test 20 min and 60 min after eating to obtain a reading of the metabolic rate by considering DIT and the RQ in the postprandial period.
- Post-op DIT increase [ Time Frame: 2 months ]A post-op increase in DIT is expected to be greater than in pre-op period and may be a positive predictor for weight loss during the post-op phase.
- Post-op RQ increase [ Time Frame: 2 months ]A postprandial increase in RQ greater than that in the pre-op phase is expected showing improvement in carbohydrate metabolism after RYGB.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01759667
|Gastrocirurgia de Brasilia|
|Brasilia, Distrito Federal, Brazil, 70390-108|
|Principal Investigator:||Silvia L Faria, M.Science||Gastrocirurgia de Brasilia|