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Bicuspid Aortic Valve Registry (BAV)

This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2016 by Dr. Bo Yang, University of Michigan
Information provided by (Responsible Party):
Dr. Bo Yang, University of Michigan Identifier:
First received: December 19, 2012
Last updated: December 21, 2016
Last verified: December 2016
The purpose of this registry is to gather information on patients with bicuspid aortic valve disease.

Bicuspid Aortic Valve

Study Type: Observational [Patient Registry]
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Target Follow-Up Duration: 30 Years
Official Title: Bicuspid Aortic Valve and Ascending Aortic Aneurysm Registry

Resource links provided by NLM:

Further study details as provided by Dr. Bo Yang, University of Michigan:

Primary Outcome Measures:
  • Characterizing patients with bicuspid aortic valve disease [ Time Frame: 30 years ]
    Identifying patients with bicuspid aortic valve disease, assessing the effect of medical intervention.

Biospecimen Retention:   Samples With DNA

Estimated Enrollment: 500
Study Start Date: April 2010
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)
Bicuspid Aortic Valve Disease Patients
Patients with the diagnosis of BAV disease.

Detailed Description:
The purpose of this registry is to gather information on patients with bicuspid aortic valve disease. The data collected in the registry will be used to assess patterns of aortic dilation, responses to medical therapy based on serial imaging and to assess for potential genetic markers of this disease

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Primary clinic

Inclusion Criteria:

  • Any patient over the age of 18 who is able/willing to give informed consent with the diagnosis of bicuspid aortic valve disease, a family history of this disease or an ascending aortic aneurysm that is idiopathic can be included in the registry.

Exclusion Criteria:

  • Patients unable or unwilling to give informed consent.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01756222

Contact: Whitney Hornsby, PhD 734-2324779

United States, Michigan
Univeristy of Michigan Recruiting
Ann Arbor, Michigan, United States, 48109
Contact: Whitney Hornsby, PhD    734-232-4779   
Sponsors and Collaborators
University of Michigan
Principal Investigator: Bo Yang, MD University of Michigan
  More Information

Responsible Party: Dr. Bo Yang, MD, University of Michigan Identifier: NCT01756222     History of Changes
Other Study ID Numbers: HUM00035836
Study First Received: December 19, 2012
Last Updated: December 21, 2016

Keywords provided by Dr. Bo Yang, University of Michigan:
Bicuspid Aortic Valve Disease
Bicuspid Aortic Valve

Additional relevant MeSH terms:
Heart Valve Diseases
Aortic Valve Stenosis
Heart Diseases
Cardiovascular Diseases
Ventricular Outflow Obstruction processed this record on May 25, 2017