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Exercise Intervention and Dexterity in Parkinson

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Marie Carmen Valenza, Universidad de Granada
ClinicalTrials.gov Identifier:
NCT01749917
First received: December 12, 2012
Last updated: November 1, 2016
Last verified: November 2016
  Purpose

The investigators conducted an intervention based in proprioceptive exercises and balance tasks. The investigators also carried out a brief intervention in manual dexterity.

The study hypothesis is that a brief intervention in upper extremities and a exercise program can increase functionality in Parkinson.


Condition Intervention
Parkinson
Other: Exercise program
Other: Control intervention

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Official Title: Therapeutic Intervention in Motor Disorders in Parkinson.

Resource links provided by NLM:


Further study details as provided by Universidad de Granada:

Primary Outcome Measures:
  • Manual dexterity [ Time Frame: baseline, 6 months ] [ Designated as safety issue: Yes ]

    Change from baseline to postintervention in dexterity. This is assessed using the Purdue Pegboard Test.

    The Purdue pegboard test is a timed physical test used to measure manual dexterity. Test subjects are asked to place small pins into holes in the pegboard using a specific hand and following a specific process.



Secondary Outcome Measures:
  • Grip strength [ Time Frame: baseline, 6 months ] [ Designated as safety issue: Yes ]

    Grip strength is measured using a Jamar dynamometer with a standard protocol allowing three attempts on each side. During each measurement, patients were sitting with their shoulder adducted and elbow flexed to 90°. The maximum value achieved from all six attempts was used in analyses.

    Kg/cm2


  • Pressure pain measure [ Time Frame: baseline, 6 months. ] [ Designated as safety issue: Yes ]
    The pressure pain threshold for each site (three points in upper extremities) is assessed using the pressure algometer. All assessments were made by the same investigator. All the subjects were trained to familiarize the subjects with the pressure algometry procedure before the measures in an anatomical site different from the chosen sites for this study.

  • Nervous assessment [ Time Frame: baseline, 6 months. ] [ Designated as safety issue: Yes ]

    Neurodynamic tests are used in upper extremities. It moves most of the nerves between the neck and hand, including the median nerve, radial and ulnar, brachial plexus, spinal nerves and cervical nerve roots.

    The patient is placed supine position. It is measured with a goniometer.


  • Risk of falls. [ Time Frame: baseline, 6 months. ] [ Designated as safety issue: Yes ]
    The risk of falls is measured with the timed up and go. It measures in seconds, the time taken by an individual to stand up from a standard arm chair,walk a distance of 3 meters, turn, walk back to the chair, and sit down.


Enrollment: 60
Study Start Date: December 2012
Study Completion Date: February 2015
Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Control group
30 people are recruited in order to the inclusion criteria for the study. The study include subjects who can complete the assessment battery of tests at the beginning and end in order to perform the control intervention.
Other: Control intervention
Active upper limb range of movement exercises for 15 minutes.
Experimental: Exercise program group
30 people are recruited, diagnosed with Parkinson attending to the Parkinson Association of Granada aged between 40 and 65 years. No sex differences. The study include subjects who can complete the assessment battery of tests at the beginning and end.
Other: Exercise program
Exercise program An brief exercise session including proprioceptive and dexterity activities
Other Name: Plaster of resistance activities

Detailed Description:
Motor symptoms in Parkinson frequently affect upper extremities. This has been associated in previous studies with limitation in the performance of activities of daily living and, consequently, with a decrease in quality of life. The possibility that a brief intervention improves eye-hand dexterity in Parkinson's, may be a therapeutic option to improve the performance of activities of daily living. The investigators also conducted an intervention based in proprioceptive exercises and balance tasks to improve functionality.
  Eligibility

Ages Eligible for Study:   40 Years to 65 Years   (Adult)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Subjects diagnosed with Parkinson attending to the Parkinson Association of Granada.
  • Subjects who can complete the assessment battery of tests at the beginning and at the end of the study.

Exclusion Criteria:

  • Auditive and visual disturbances.
  • Cognitive problems.
  • Psychiatric pathology.
  • Sensorial disturbances.
  • Traumatic pathology of the hand.
  • Concomitant neurological conditions.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01749917

Locations
Spain
Faculty of Health Sciences. University of Granada.
Granada, Andalucia, Spain, 18071
Sponsors and Collaborators
Universidad de Granada
Investigators
Principal Investigator: M. Carmen Valenza, PH MD Department of Physical Therapy. University of Granada.
  More Information

Publications:
Responsible Party: Marie Carmen Valenza, Assistant professor, Universidad de Granada
ClinicalTrials.gov Identifier: NCT01749917     History of Changes
Other Study ID Numbers: DF0036UG 
Study First Received: December 12, 2012
Last Updated: November 1, 2016
Health Authority: Spain: Comité Ético de Investigación Clínica
Individual Participant Data  
Plan to Share IPD: Undecided

Keywords provided by Universidad de Granada:
Parkinson.
Dexterity.
Balance.
Exercises.

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on December 09, 2016