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Music Listening and Stroke Recovery (MUKU2)

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ClinicalTrials.gov Identifier: NCT01749709
Recruitment Status : Unknown
Verified June 2013 by Turku University Hospital.
Recruitment status was:  Recruiting
First Posted : December 17, 2012
Last Update Posted : June 25, 2013
Academy of Finland
Information provided by (Responsible Party):
Turku University Hospital

Brief Summary:
Clinical study including 60 subjects to investigate the effect of daily music listening on stress parameters during the acute phase of stroke and on recovery. 20 subjects listen to instrumentala music, 20 listen to music with lyrics and 20 are controls. Outcome measures in the acute phase are levels of physiological stress parameters (cortisol, endorphin, oxytocin). Outcome measures in the recovery phase are cognitive capabilities and mood measured with standard clinical tests. Follow-up time is 6 months.

Condition or disease Intervention/treatment
Stroke Behavioral: Music listening

Detailed Description:
Please see above

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effect of Cognitive Stimulation on Recovery After Stroke
Study Start Date : December 2012
Estimated Primary Completion Date : December 2014
Estimated Study Completion Date : December 2014

Arm Intervention/treatment
Experimental: Instrumental music listening
Daily music listening
Behavioral: Music listening
Experimental: Vocal music listening
Daily music listening
Behavioral: Music listening
No Intervention: control
Standard rehabilitation

Primary Outcome Measures :
  1. physiological stress indicator [ Time Frame: Within two weeks after stroke ]
    cortisol, beta-endoprhin and oxytocin concentration in salivary samples

  2. Neuropsychological performance [ Time Frame: up to 6 months ]
    Standard neuropsychological test battery

  3. Brain MRI [ Time Frame: up to 6 months ]

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Acute Hemispheral stroke

Exclusion Criteria:

  • Previous neurological or current psychiatric disease,
  • severe aphasia

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01749709

Contact: Seppo Soinila, MD seppo.soinila@tyks.fi

Turku University Hospital Recruiting
Turku, Finland
Contact: Seppo Soinila, Prof.         
Sponsors and Collaborators
Turku University Hospital
Academy of Finland

Responsible Party: Turku University Hospital
ClinicalTrials.gov Identifier: NCT01749709     History of Changes
Other Study ID Numbers: 85/180/2011
First Posted: December 17, 2012    Key Record Dates
Last Update Posted: June 25, 2013
Last Verified: June 2013

Keywords provided by Turku University Hospital:

Additional relevant MeSH terms:
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases