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Music Listening and Stroke Recovery (MUKU2)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2013 by Turku University Hospital.
Recruitment status was:  Recruiting
Academy of Finland
Information provided by (Responsible Party):
Turku University Hospital Identifier:
First received: December 12, 2012
Last updated: June 24, 2013
Last verified: June 2013
Clinical study including 60 subjects to investigate the effect of daily music listening on stress parameters during the acute phase of stroke and on recovery. 20 subjects listen to instrumentala music, 20 listen to music with lyrics and 20 are controls. Outcome measures in the acute phase are levels of physiological stress parameters (cortisol, endorphin, oxytocin). Outcome measures in the recovery phase are cognitive capabilities and mood measured with standard clinical tests. Follow-up time is 6 months.

Condition Intervention
Stroke Behavioral: Music listening

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effect of Cognitive Stimulation on Recovery After Stroke

Further study details as provided by Turku University Hospital:

Primary Outcome Measures:
  • physiological stress indicator [ Time Frame: Within two weeks after stroke ]
    cortisol, beta-endoprhin and oxytocin concentration in salivary samples

  • Neuropsychological performance [ Time Frame: up to 6 months ]
    Standard neuropsychological test battery

  • Brain MRI [ Time Frame: up to 6 months ]

Estimated Enrollment: 60
Study Start Date: December 2012
Estimated Study Completion Date: December 2014
Estimated Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Instrumental music listening
Daily music listening
Behavioral: Music listening
Experimental: Vocal music listening
Daily music listening
Behavioral: Music listening
No Intervention: control
Standard rehabilitation

Detailed Description:
Please see above

Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Acute Hemispheral stroke

Exclusion Criteria:

  • Previous neurological or current psychiatric disease,
  • severe aphasia
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01749709

Contact: Seppo Soinila, MD

Turku University Hospital Recruiting
Turku, Finland
Contact: Seppo Soinila, Prof.         
Sponsors and Collaborators
Turku University Hospital
Academy of Finland
  More Information

Responsible Party: Turku University Hospital Identifier: NCT01749709     History of Changes
Other Study ID Numbers: 85/180/2011
Study First Received: December 12, 2012
Last Updated: June 24, 2013

Keywords provided by Turku University Hospital:

Additional relevant MeSH terms:
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases processed this record on September 21, 2017