Expanding Antimicrobial Stewardship

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01746888
Recruitment Status : Completed
First Posted : December 11, 2012
Last Update Posted : November 8, 2013
Information provided by (Responsible Party):
Jeffrey Caterino, Ohio State University

Brief Summary:
Gold standard diagnostic criteria for diagnosing acute infection in older adult patients in the Emergency Department do not currently exist. These patients often have atypical presentations which can complicate diagnosis and treatment. The development of an antimicrobial stewardship program for Emergency Department older adult patients can ultimately improve the accuracy of diagnosis and correct antimicrobial prescribing. This research study involves data collection from enrolled subjects and treating physicians. The data will be collected using a patient interview which will be answered directly by the patient or caregiver. Additional surveys will be administered to the Emergency Department treating physician and subsequent physician. Additional data will be abstracted from the Emergency Department chart and from additional charts that often accompanies the patient to the Emergency Department. A physician adjudication process will occur if there is disagreement in diagnosis between the treating Emergency Department physician and succeeding physician.

Condition or disease

Study Type : Observational
Actual Enrollment : 437 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Expanding Antimicrobial Stewardship
Study Start Date : August 2011
Actual Primary Completion Date : August 2013
Actual Study Completion Date : August 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Antibiotics

Older Adults
Adults 65 years and older who present to the Emergency Department.

Primary Outcome Measures :
  1. Presence of infection while in the Emergency Department [ Time Frame: participants will be followed for the duration of hospital stay, an expected average of 4 days. ]

Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Adults 65 years of age and older who present to the Emergency Department.

Inclusion Criteria:

  • 65 years of age

Exclusion Criteria:

  • Patient incarcerated
  • Chief complaint of suicidal or homicidal ideation
  • Patient primarily evaluated by the trauma team

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01746888

United States, Ohio
Wexner Medical Center at The Ohio State University
Columbus, Ohio, United States, 43210
Sponsors and Collaborators
Jeffrey Caterino
Principal Investigator: Jeffrey M Caterino, MD, MPH Ohio State University

Responsible Party: Jeffrey Caterino, Associate Professor, Ohio State University Identifier: NCT01746888     History of Changes
Other Study ID Numbers: 2011H0165
First Posted: December 11, 2012    Key Record Dates
Last Update Posted: November 8, 2013
Last Verified: November 2013

Additional relevant MeSH terms:
Anti-Infective Agents
Anti-Bacterial Agents