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Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography (ATAC)

This study is currently recruiting participants. (see Contacts and Locations)
Verified January 2017 by The Cleveland Clinic
Information provided by (Responsible Party):
Sunil Srivastava, The Cleveland Clinic Identifier:
First received: December 7, 2012
Last updated: January 10, 2017
Last verified: January 2017
A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Automated Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

Resource links provided by NLM:

Further study details as provided by The Cleveland Clinic:

Primary Outcome Measures:
  • Use the OCT to objectively image and grade the degree of anterior chamber inflammation in eyes with inactive and active uveitis. [ Time Frame: one year ]

Estimated Enrollment: 1500
Study Start Date: June 2012
Estimated Study Completion Date: June 2018
Estimated Primary Completion Date: June 2018 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients with inactive and active uveitis.

Inclusion Criteria:

  • All patients presenting to Cole Eye Institute with uveitis.

Exclusion Criteria:

  • Inability to provide informed consent, including non-English speaking and cognitively/mentally impaired.
  • Severe corneal opacities preventing imaging of anterior chamber
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01746537

Contact: Sunil K Srivastava, M.D. 216-636-2286
Contact: Kimberly M Baynes, BSN, RN 216-44-2566

United States, Ohio
Cole Eye Institute Recruiting
Cleveland, Ohio, United States, 44195
Contact: Sunil K Srivastava, M.D.    216-636-2286      
Contact: Kimberly M Baynes, BSN,RN    216-444-2566      
Principal Investigator: Sunil K Srivastava, M.D.         
Sponsors and Collaborators
The Cleveland Clinic
Principal Investigator: Sunil K Srivastva, MD The Cleveland Clinic
  More Information

Responsible Party: Sunil Srivastava, Medical Doctor, The Cleveland Clinic Identifier: NCT01746537     History of Changes
Other Study ID Numbers: 12-612
Study First Received: December 7, 2012
Last Updated: January 10, 2017

Additional relevant MeSH terms:
Pathologic Processes
Uveal Diseases
Eye Diseases processed this record on April 26, 2017