Gastrointestinal Motility in Severe Ulcerative Colitis Obtained by Motilis-3D-transit
Recruitment status was Recruiting
The purpose of this study is to describe gastrointestinal (GI) motility in patients suffering from severe Ulcerative Colitis (UC) and to compare these results with similar results obtained in remission.
The study is done with the use of Motilis 3D-Transit system which consists of a small electronic capsule ingested and detected by a receiver carried by the patient. Position and orientation of the capsule are interpreted by dedicated computer software and transit times, progression velocity and contraction frequencies can be revealed.
The study is mainly descriptive and is designed to test and evaluate the usefulness of the Motilis 3D Transit system in UC patients and to tell investigators more about GI motility during and after severe inflammation.
Motilis 3D-Transit system gives investigators a unique chance to study the gastrointestinal canal as a whole during and after severe illness.
The investigators expect to include 20 patients suffering from severe UC admitted to Hospital with the purpose of getting medical treatment. The investigators do not expect any drop out, but in case of drop out a new patient will be included.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Gastrointestinal Motility in Patients Suffering From Severe Ulcerative Colitis Obtained by Motilis-3D-transit|
- Velocity of progression through the inflamed part of the colon in severe UC compared to the velocity of progression in the corresponding colonic segment in quiescent UC. [ Time Frame: Three days from baseline visit ] [ Designated as safety issue: No ]
- Velocity of progression through the non-inflamed colonic segments in severe UC compared to the velocity of progression in the corresponding colonic segments in quiescent UC. [ Time Frame: Three days from baseline ] [ Designated as safety issue: No ]
- Velocity of progression through the colonic segments in quiescent UC compared to the velocity of progression in the corresponding colonic segments in healthy volunteers. [ Time Frame: three days from baseline visit ] [ Designated as safety issue: No ]
|Study Start Date:||April 2013|
|Estimated Study Completion Date:||March 2015|
|Estimated Primary Completion Date:||April 2014 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01745029
|Contact: AnneMette Haase, ph.d student||+45 firstname.lastname@example.org|
|Contact: Klaus Krogh, Professor||+45 2338 email@example.com|
|Aarhus University Hospital, Department of Hepato and Gastroenterolegy||Recruiting|
|Aarhus C, Denmark, 8000|
|Contact: AnneMette Haase, Ph.d Student +45 6165 8483 firstname.lastname@example.org|
|Principal Investigator: AnneMette Haase, Ph.d Student|