Assessment of Needs of Moisturizers After Various Laser Treatments

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Pusan National University Hospital
ClinicalTrials.gov Identifier:
NCT01742247
First received: December 3, 2012
Last updated: March 29, 2016
Last verified: March 2016
  Purpose
Assessment of needs of moisturizers after various laser treatments

Condition Intervention Phase
Dermatologic Disorders
Injury Due to Laser
Other: Physiogel
Other: Moisturizer
Phase 4

Study Type: Interventional
Study Design: Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Phase 4 Study of Assessment of Needs of Moisturizers After Various Laser Treatment

Resource links provided by NLM:


Further study details as provided by Pusan National University Hospital:

Primary Outcome Measures:
  • Clinical assessment of erythema, transepidermal water loss [ Time Frame: 2weeks ] [ Designated as safety issue: No ]
    The clinical assessment of erythema, pigmentation, transepidermal water loss will be evaluated by using apparatus.


Enrollment: 20
Study Start Date: September 2012
Study Completion Date: December 2015
Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Physiogel, Laser therapy, Moisturizer

Experimental: Physiogel treated & Non-treated

1 Palmitoylethanolamide, Physiogel 3 times a day for 2 weeks

Other: Physiogel
Application of moisturizer on laser-treated area
Other Names:
  • Other moisturizer: Palmitoylethanolamide
  • Other Names:Physiogel
Other: Moisturizer
Application of moisturizer on laser-treated area
Other Names:
  • Other moisturizer: Palmitoylethanolamide
  • Other Names:Physiogel

Detailed Description:

The investigators would like to assess of needs of moisturizers after various laser treatment

: by investigating the changes in the skin barrier function after fractional carbon dioxide laser and fractional Er:Glass laser in mice and human skin

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • at least 18 years of age without any dermatologic diseases

Exclusion Criteria:

  • Taking other known dermatologic disease
  • Others who are shown pigmented lesion on treated-area
  • Who have allergy or history of hypersensitivity reaction to moisturizers
  • Who have other definitive cutaneous findings
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01742247

Locations
Korea, Republic of
Department of dermatology, Pusan National University Hospital
Busan, Korea, Republic of
Sponsors and Collaborators
Pusan National University Hospital
Investigators
Study Chair: Byung-Soo Kim, Ph.D. Pusna National University Hospital
  More Information

Responsible Party: Pusan National University Hospital
ClinicalTrials.gov Identifier: NCT01742247     History of Changes
Other Study ID Numbers: PNUHDM-laser and moisturizers 
Study First Received: December 3, 2012
Last Updated: March 29, 2016
Health Authority: Korea: Institutional Review Board

Keywords provided by Pusan National University Hospital:
Moisturizer, laser

Additional relevant MeSH terms:
Skin Diseases
Palmidrol
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Anti-Inflammatory Agents
Antirheumatic Agents
Antiviral Agents
Anti-Infective Agents
Cannabinoid Receptor Agonists
Cannabinoid Receptor Modulators
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists

ClinicalTrials.gov processed this record on July 27, 2016