THE ASSOCIATION BETWEEN FATTY LIVER (NAFLD) DISEASE AND PCOS
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|ClinicalTrials.gov Identifier: NCT01735799|
Recruitment Status : Unknown
Verified November 2012 by Assy Nimer, Ziv Hospital.
Recruitment status was: Not yet recruiting
First Posted : November 28, 2012
Last Update Posted : November 28, 2012
Since both pathologies (PCOS and NAFLD) involve disturbed carbohydrate economy, which revolve around insulin resistance, it is tempting to examine the specific "liver profile" of women with PCOD. Furthermore, it would be of great importance if lean women who suffer from PCOD would be revealed to shere cardiovascular risks with their more overweight peers.
Patients - women who will be diagnosed with PCOD following their initial referal to our fertility clinic. Controls - normal ovulatory women who approached our fertility clinic due to either unexplained or male factor infertility.
Workup - history for menstrual pattern; Clinical evaluation for features of hyperandrogenism; ultrasonographic documentation of ovarian morphology; follicular phase hormonal profile for validation of the diagnosis and for ruling out other pathologies which may cause anovulation.
Liver profiling - The following blood tests will be used for the biochemical profiling: fasting glucose and insulin, CRP, HDL-cholesterol, triglycerides, AST, ALT, GGT, LDH, alkaline phosphatase, total bilirubin, direct bilirubin, ferritin, HBA1C and micro albumin ratio.
FibroScan® will be used to measure liver stiffness.
|Condition or disease|
|Polycystic Ovarian Syndrome, Nonalcoholic Fatty Liver Disease|
|Study Type :||Observational|
|Study Start Date :||November 2012|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01735799
|Contact: Nimer Assy, MDfirstname.lastname@example.org|
|Liver Clinic, ZIv Medical Center||Not yet recruiting|
|Safed, Israel, 13100|
|Contact: Nimer Assy, MD +972-4-6828445 email@example.com|