Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
The purpose of this study is to determine the changes in quality of life and degree of tremor for patients with essential tremor or Parkinsonian tremor who are treated by stereotactic radiosurgery (SRS). This is a questionnaire-based study. Please see Detailed Description below for more information.
Quality of Life
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor|
- Quality of Life [ Time Frame: 1 year ] [ Designated as safety issue: No ]The tremor-related quality of life for each patient will be assessed by self-assessment questionnaire at 3 month intervals for 1 year after treatment by stereotactic radiation.
- Severity of Tremor [ Time Frame: 1 year ] [ Designated as safety issue: No ]The severity of tremor will be assessed by objective measure (Fahn-Tolosa-Marin tremor rating scale) at 3 month intervals for 1 year following the stereotactic radiation treatment.
- Neuropsychological Assessment [ Time Frame: Baseline and 6 months post-treatment ] [ Designated as safety issue: No ]All patients will undergo a neuropsychological assessment (1-2 hr examination) at baseline and at 6 months post-treatment. This will assess any unanticipated changes in neuropsychological brain function.
|Study Start Date:||November 2012|
|Estimated Study Completion Date:||November 2017|
|Estimated Primary Completion Date:||November 2016 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01734122
|United States, Tennessee|
|Vanderbilt University Medical Center||Recruiting|
|Nashville, Tennessee, United States, 37232|
|Contact: Send Patient Referrals to Movement Disorder Coordinators 615-322-0141 ext Fax 6153436847|
|Contact: Vanderbilt University Radiation Oncology (nursing staff) 615-343-2624|
|Principal Investigator: Austin N. Kirschner, MD, PhD|
|Principal Investigator: Anthony J. Cmelak, MD|
|Sub-Investigator: Joseph S. Neimat, MD|
|Sub-Investigator: Fenna T. Phibbs, MD, MPH|
|Sub-Investigator: Peter Hedera, MD|
|Sub-Investigator: Scott A Wylie, PhD|