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Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections

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ClinicalTrials.gov Identifier: NCT01731483
Recruitment Status : Unknown
Verified November 2012 by Peter Verhamme, Universitaire Ziekenhuizen Leuven.
Recruitment status was:  Recruiting
First Posted : November 21, 2012
Last Update Posted : November 21, 2012
Sponsor:
Information provided by (Responsible Party):
Peter Verhamme, Universitaire Ziekenhuizen Leuven

Brief Summary:
the aim of this study is to investigate the role of staphylokinase, streptokinase and MMP activation in invasive staphylococcal and streptococcal infections.

Condition or disease
Coagulation Fibrinolysis

Study Type : Observational
Estimated Enrollment : 130 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections.
Study Start Date : July 2012
Estimated Primary Completion Date : July 2015

Resource links provided by the National Library of Medicine

U.S. FDA Resources




Biospecimen Retention:   Samples Without DNA
tissue specimens from endocarditis lesions and necrotizing fasciitis


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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Material will be collected from all patients that undergo surgical treatment for invasive streptococcal or staphylococcal infections, including acute infective endocarditis and necrotizing fasciitis, from the UZ Leuven University Hospital
Criteria

Inclusion Criteria:

  • all patients that undergo surgical treatment for invasive streptococcal or staphylococcal infections, including acute infective endocarditis and necrotizing fasciitis, from the UZ Leuven University Hospital

Exclusion Criteria:


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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01731483


Locations
Belgium
UZ Leuven University Hospital Recruiting
Leuven, Belgium, 3000
Contact: Peter Verhamme, Prof.    +32 16 34 34 91      
Principal Investigator: Peter Verhamme, Prof.         
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven

Responsible Party: Peter Verhamme, Prof. Verhamme, Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT01731483     History of Changes
Other Study ID Numbers: M-1
First Posted: November 21, 2012    Key Record Dates
Last Update Posted: November 21, 2012
Last Verified: November 2012

Keywords provided by Peter Verhamme, Universitaire Ziekenhuizen Leuven:
virulence factors

Additional relevant MeSH terms:
Streptococcal Infections
Gram-Positive Bacterial Infections
Bacterial Infections