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Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2012 by Peter Verhamme, Universitaire Ziekenhuizen Leuven.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01731483
First Posted: November 21, 2012
Last Update Posted: November 21, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Peter Verhamme, Universitaire Ziekenhuizen Leuven
  Purpose
the aim of this study is to investigate the role of staphylokinase, streptokinase and MMP activation in invasive staphylococcal and streptococcal infections.

Condition
Coagulation Fibrinolysis

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections.

Resource links provided by NLM:


Further study details as provided by Peter Verhamme, Universitaire Ziekenhuizen Leuven:

Biospecimen Retention:   Samples Without DNA
tissue specimens from endocarditis lesions and necrotizing fasciitis

Estimated Enrollment: 130
Study Start Date: July 2012
Estimated Primary Completion Date: July 2015 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Material will be collected from all patients that undergo surgical treatment for invasive streptococcal or staphylococcal infections, including acute infective endocarditis and necrotizing fasciitis, from the UZ Leuven University Hospital
Criteria

Inclusion Criteria:

  • all patients that undergo surgical treatment for invasive streptococcal or staphylococcal infections, including acute infective endocarditis and necrotizing fasciitis, from the UZ Leuven University Hospital

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01731483


Locations
Belgium
UZ Leuven University Hospital Recruiting
Leuven, Belgium, 3000
Contact: Peter Verhamme, Prof.    +32 16 34 34 91      
Principal Investigator: Peter Verhamme, Prof.         
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven
  More Information

Responsible Party: Peter Verhamme, Prof. Verhamme, Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT01731483     History of Changes
Other Study ID Numbers: M-1
First Submitted: November 15, 2012
First Posted: November 21, 2012
Last Update Posted: November 21, 2012
Last Verified: November 2012

Keywords provided by Peter Verhamme, Universitaire Ziekenhuizen Leuven:
virulence factors

Additional relevant MeSH terms:
Streptococcal Infections
Gram-Positive Bacterial Infections
Bacterial Infections