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The Learning and Memory of the Experience of Pain

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Jian Kong, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT01731314
First received: November 16, 2012
Last updated: August 28, 2017
Last verified: June 2015
  Purpose
This study investigates the learning and memory of pain.

Condition Intervention
Pain Behavioral: Learning and Memory of Pain

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single (Participant)
Primary Purpose: Other

Resource links provided by NLM:


Further study details as provided by Jian Kong, Massachusetts General Hospital:

Estimated Enrollment: 60
Study Start Date: January 2013
Estimated Study Completion Date: January 2019
Estimated Primary Completion Date: January 2018 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. Male and female healthy volunteers.
  2. 18-65 years of age.
  3. Right-handed.
  4. Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

Exclusion Criteria:

  1. Any previous experience with conditioned analgesia/hyperalgesia paradigms.
  2. Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
  3. Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
  4. Instability of responses to experimental heat pain
  5. Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
  6. Peripheral neuropathy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01731314

Locations
United States, Massachusetts
MGH East Campus, 149 13th St.
Charlestown, Massachusetts, United States, 02129
Sponsors and Collaborators
Massachusetts General Hospital
  More Information

Responsible Party: Jian Kong, MS, MD, Massachusetts General Hospital
ClinicalTrials.gov Identifier: NCT01731314     History of Changes
Other Study ID Numbers: 2012P002386
Study First Received: November 16, 2012
Last Updated: August 28, 2017

ClinicalTrials.gov processed this record on September 21, 2017