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The Learning and Memory of the Experience of Pain

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2015 by Jian Kong, Massachusetts General Hospital.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Jian Kong, Massachusetts General Hospital Identifier:
First received: November 16, 2012
Last updated: June 8, 2015
Last verified: June 2015
This study investigates the learning and memory of pain.

Condition Intervention
Pain Behavioral: Learning and Memory of Pain

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Single Blind (Participant)

Resource links provided by NLM:

Further study details as provided by Jian Kong, Massachusetts General Hospital:

Estimated Enrollment: 60
Study Start Date: January 2013
Estimated Study Completion Date: December 2016
Estimated Primary Completion Date: January 2016 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  1. Male and female healthy volunteers.
  2. 18-65 years of age.
  3. Right-handed.
  4. Fluency in English. Ability to read and understand English; English can be a second language provided that the participant feels that he/she is able to understand all the questions used in the assessment measures.

Exclusion Criteria:

  1. Any previous experience with conditioned analgesia/hyperalgesia paradigms.
  2. Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder according to the DSM-IV manual, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
  3. Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
  4. Instability of responses to experimental heat pain
  5. Any contraindications to fMRI scanning for subjects in Experiment 2 (including metal implants, claustrophobia, history of head trauma, and pregnancy).
  6. Peripheral neuropathy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01731314

Contact: Sharon Sun 617-726-5004

United States, Massachusetts
MGH East Campus, 149 13th St. Recruiting
Charlestown, Massachusetts, United States, 02129
Contact: Natalia Egorova, PhD   
Sponsors and Collaborators
Massachusetts General Hospital
  More Information

Responsible Party: Jian Kong, MS, MD, Massachusetts General Hospital Identifier: NCT01731314     History of Changes
Other Study ID Numbers: 2012P002386
Study First Received: November 16, 2012
Last Updated: June 8, 2015 processed this record on June 23, 2017