Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Effect of Regular Exercise on Maternal Cardiovascular System During Pregnancy

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2014 by Technical University of Madrid.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
María Perales Santaella, Technical University of Madrid Identifier:
First received: November 5, 2012
Last updated: November 13, 2014
Last verified: March 2014
The main aim of this study was to analysed the security of a supervised exercise program on maternal cardiovascular system and assess the positive effects of this program on maternal cardiovascular function and structure

Condition Intervention
Behavioral: Exercise group

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Supportive Care
Official Title: Effect of Supervised Exercise Program on Cardiovascular Function and Structure in Pregnant Women. Randomized Controlled Trial

Resource links provided by NLM:

Further study details as provided by Technical University of Madrid:

Primary Outcome Measures:
  • Change from cardiovascular function at the end of pregnancy: Stroke volume [ Time Frame: Weeks 20 and 34 ]
    Data were collected in second and third trimester

  • Change from cardiovascular structure at the end of the pregnancy [ Time Frame: Weeks 20 and 34 ]
    Data were collected in second and third trimester

Secondary Outcome Measures:
  • Maternal and fetal pregnancy outcomes [ Time Frame: During pregnancy. At the moment of delivery. ]
    Gestational age, type of delivery, duration of labor, maternal weight gain, birth weight, size and head circumference of new born, pH of umbilical cord, Apgar Score.

Estimated Enrollment: 800
Study Start Date: February 2009
Estimated Study Completion Date: September 2015
Primary Completion Date: June 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Control
Sedentary pregnant women
Experimental: Exercise group Behavioral: Exercise group

Supervised physical conditioning program of three 55—60 minute sessions per week during whole pregnancy (from week 9 to 38). Each session consists of 25-30 minutes of cardiovascular exercise,10 minutes of specific exercises (strength and balance exercises), and 10 minutes of pelvic floor muscles training

Aerobic activity was prescribed at light to moderate intensity, aiming for 55-60 of maximal heart rate. All subjects wore a heart rate (HR) monitor (Polar FT7) during the training sessions to ensure that exercise intensity was light to moderate.

Detailed Description:

During pregnancy, the effectiveness of cardiovascular system is necessary to the growth and development of the baby, however many changes in it occur during this period.

Physical exercise has shown to have a positive effect on cardiovascular structure and function in the general population.


Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Being healthy and able to exercise following American College of Obstetricians and Gynecologists (ACOG) guidelines
  • Being able to communicate in spanish
  • Giving birth at Hospital Universitario de Fuenlabrada and Hospital Universitario Severo Ochoa (Madrid).

Exclusion Criteria:

  • Multiparity
  • Obstetrician complications
  • Being interested in the study after 18 weeks
  • Not being regular in physical exercise program
  • Younger than 18 years old
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01723098

Contact: Maria Perales, PhD student 913364081
Contact: Ruben Barakat, PhD 913364120

Universidad Politecnica de Madrid Recruiting
Madrid, Spain, 28040
Contact: Maria Perales, PhD student    913364081   
Contact: Ruben Barakat, PhD    913364120   
Principal Investigator: Maria Perales, PhD student         
Sponsors and Collaborators
Technical University of Madrid
Study Director: Ruben Barakat, PhD Universidad Politecnica de Madrid
  More Information

Responsible Party: María Perales Santaella, PhD Student, Technical University of Madrid Identifier: NCT01723098     History of Changes
Other Study ID Numbers: Maternal cardiovascular system
Study First Received: November 5, 2012
Last Updated: November 13, 2014

Keywords provided by Technical University of Madrid:
Pregnancy, cardiovascular system, physical exercise processed this record on May 24, 2017