Pakistan Epidemiological Survey in Acute Pharyngitis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01720927
Recruitment Status : Completed
First Posted : November 2, 2012
Last Update Posted : September 15, 2014
Isra University
Information provided by (Responsible Party):
Suresh Kumar, Hill Park General Hospital

Brief Summary:

GABHS are common etiological agents for acute pharyngitis. However, local data is limited and large scale surveillance studies have not been done. This study aims to evaluate the disease burden in the community due to GABHS.

In this study, patients presenting with signs of acute pharyngitis will be evaluated. Patients with fulfilling the inclusion criteria will be tested for Rapid Antigen Detection test (RADT)

Condition or disease
Acute Pharyngitis

  Show Detailed Description

Study Type : Observational
Actual Enrollment : 5140 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Pakistan Epidemiological Survey in Acute Pharyngitis
Study Start Date : November 2012
Actual Primary Completion Date : November 2013
Actual Study Completion Date : November 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sore Throat

Acute Pharyngitis
Subjects presenting with acute pharyngitis

Primary Outcome Measures :
  1. To evaluate the prevalence of GABHS in patients with acute pharyngitis. [ Time Frame: 12 months ]

Secondary Outcome Measures :
  1. To study the prevalence of GABHS in acute pharyngitis across different age groups. [ Time Frame: 12 months ]
  2. To study the correlation of centor score and RADT results. [ Time Frame: 12 months ]

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Ages Eligible for Study:   3 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The study population will include children and adults presenting with sore throat, temperature greater than 100.40 F, tonsillar exudates and cervical adenopathy will be included.

Inclusion Criteria:

  • Male and female subjects with signs of acute pharyngitis (duration of symptoms < 14 days)
  • Subjects with sore throat
  • Fever with sudden onset (temperature > 100 0 F (380 C)
  • Exposure to Streptococcus within the preceding 2 weeks
  • Children 3 years of age and above
  • Subjects / guardians giving written authorization to participate in the study

Exclusion Criteria:

  • Recurrent or persistent cases of sore throat
  • Complicated pharyngitis (peritonsillar abscesses, Lemierre disease, Vincent's angina)
  • Severe comorbidity
  • Immunosuppression or history of acute rheumatic fever
  • Special circumstances, such as sore throat after travel in past 2 weeks, sore throat linked to sexual transmission or rare epidemics (e.g. diphtheria)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01720927

ISRA University
Hyderabad, Sind, Pakistan
Sponsors and Collaborators
Suresh Kumar
Isra University

Responsible Party: Suresh Kumar, Investigator, Hill Park General Hospital Identifier: NCT01720927     History of Changes
Other Study ID Numbers: PK-12-02
First Posted: November 2, 2012    Key Record Dates
Last Update Posted: September 15, 2014
Last Verified: September 2014

Keywords provided by Suresh Kumar, Hill Park General Hospital:
Acute Pharyngitis, GABHS

Additional relevant MeSH terms:
Pharyngeal Diseases
Stomatognathic Diseases
Respiratory Tract Infections
Respiratory Tract Diseases
Otorhinolaryngologic Diseases