Functional MRI of Stress in Obesity
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01719484 |
Recruitment Status
:
Active, not recruiting
First Posted
: November 1, 2012
Last Update Posted
: March 13, 2018
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease |
---|
Obesity |
Study Type : | Observational |
Estimated Enrollment : | 60 participants |
Observational Model: | Case-Control |
Time Perspective: | Prospective |
Official Title: | Functional Magnetic Resonance Imaging of Stress in Obesity |
Study Start Date : | May 2008 |
Actual Primary Completion Date : | May 2015 |
Estimated Study Completion Date : | May 2019 |
Group/Cohort |
---|
Healthy
Subjects deemed to be medically healthy
|
Obese
Subjects deemed to be medically obese
|
- No outcome measures for this study, this is an imaging study only [ Time Frame: Upon study completion ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years to 50 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- Between ages 18-50 years old.
- Able to read and write.
- negative urine toxicology screens during intake appointments indicating no history of current or past dependence on alcohol or illicit drug use.
- WOMEN: have a regular menstrual cycle.
- BMI: 30 < BMI < 35 for obese subjects (upper limit of 35 selected given our experience with heavier individuals fitting comfortably in the fMRI scanner) and 18.5 < BMI <25 for normal weight subjects (Institute, 2006)
Exclusion Criteria:
- any major neurological illness or injury and any current or prior clinically significant mental health (including PTSD) or substance use disorder (with exception of nicotine dependence) as determined by SCID interview;
- Regular use of any psychoactive drugs including anxiolytics and antidepressants.
- Any significant current medical condition such as neurological, cardiovascular, endocrine, renal, liver, thyroid pathology; subjects on medications for any medical condition will be excluded.
- Any subjects with foreign ferromagnetic metal objects in their body or other MR contraindications will be excluded including subjects who work as welders.
- Women on oral contraceptives, peri- and post-menopausal women, and pregnant or lactating women (as alterations in stress response are associated with these states).

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01719484
United States, Connecticut | |
Yale University School of Medicine | |
New Haven, Connecticut, United States, 06519 |
Principal Investigator: | Marc N Potenza, MD, PhD | Yale University |
Responsible Party: | Yale University |
ClinicalTrials.gov Identifier: | NCT01719484 History of Changes |
Other Study ID Numbers: |
0805003899 |
First Posted: | November 1, 2012 Key Record Dates |
Last Update Posted: | March 13, 2018 |
Last Verified: | March 2018 |
Additional relevant MeSH terms:
Obesity Overnutrition Nutrition Disorders |
Overweight Body Weight Signs and Symptoms |