Early Detection of Lung Cancer and Mesothelioma in Workers Exposed to Asbestos
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01719068
Recruitment Status : Unknown
Verified October 2012 by British Columbia Cancer Agency. Recruitment status was: Recruiting
This is a pilot study that aims to develop a lung cancer screening program for workers in British Columbia, Canada exposed to asbestos who are at risk of developing lung cancer/pleural mesothelioma. This is high risk population is at of respiratory system diseases as a result of their occupational exposures. Additionally, knowledge garnered from this study will allow us to develop other studies that will further our understanding of asbestos related lung cancer and mesothelioma.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Layout table for eligibility information
Ages Eligible for Study:
50 Years to 79 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Workers in British Columbia who have been exposed to asbestos.
Women or men age 50 to 79 years
history of exposure to asbestos at work and one or more of the following:
lung cancer risk ≥2% over 3 years or
asbestosis or pleural plaques on a chest x-ray or
abnormal auto-antibodies level using the EarlyCDT test
Capable of providing informed consent for screening procedures (low dose spiral CT, lung function, blood biomarkers).
Any medical condition, such as severe heart disease (e.g. unstable angina, chronic congestive heart failure), acute or chronic respiratory failure, or any disorder, that in the opinion of the physician unlikely to benefit from screening due to shortened life-expectancy from co-existing illnesses
Have been previously diagnosed with mesothelioma
Have had other cancer within the past 5 years with the exception of the following cancers: non-melanomatous skin cancer,localized prostate cancer, carcinoma in situ (CIS) of the cervix, or superficial bladder cancer. Treatment of the exceptions must have ended >6 months before registration into this study