Periodontal Disease Treatment of a Physically Challenged Population (PDT)
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|ClinicalTrials.gov Identifier: NCT01718912|
Recruitment Status : Completed
First Posted : October 31, 2012
Last Update Posted : March 31, 2016
Many physically handicapped patients at the dental department, Toronto Rehabilitation Institute(TRI) have considerable gingival inflammation and breath odour because of the inability to effectively handle a toothbrush. These patients have considerable periodontal disease. There is a concern that these pathogens may have a detrimental effect on wound healing in other areas of the body.
Hypothesis: Patients attending the dental department at TRI that are treated with the antibiotic-antifungal rinse containing metronidazole and nystatin will show substantial decrease in periodontal disease as measured by bleeding points and pocket depth when compared to the group that continues to use their regular oral hygiene methods (control group).
|Condition or disease||Intervention/treatment||Phase|
|Periodontal Disease||Drug: metronidazole-nystatin oral rinse||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||11 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||The Effect of an Antibiotic-antifungal Rinse on Periodontal Disease|
|Study Start Date :||November 2013|
|Actual Primary Completion Date :||September 2014|
|Actual Study Completion Date :||October 2014|
Metronidazole-nystatin oral rinse, regular oral hygiene
Week 1: daily brushing with suction brush. Week two: daily brushing with a mixture of metronidazole-nystatin suspension.
|Drug: metronidazole-nystatin oral rinse|
- Evidence of healing of periodontal tissues as shown by a reduction of bleeding [ Time Frame: two weeks ]Evidence of healing of periodontal tissues is assessed by measuring bleeding points and periodontal pocket depth using a dental probe.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01718912
|Toronto Rehabilitation Institute, Dental Department|
|Toronto, Ontario, Canada, M5G 2A2|