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The Effects of Cordyceps Sinensis and Lingzhi on Cardiovascular Fitness and Cognitive Function

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified October 2012 by Hillel Yaffe Medical Center.
Recruitment status was:  Not yet recruiting
Information provided by (Responsible Party):
Hillel Yaffe Medical Center Identifier:
First received: October 29, 2012
Last updated: NA
Last verified: October 2012
History: No changes posted
Cordyceps Sinensis (CS) and Lingzhi extracts have been used in Chinese Medicine for many years for treatment of a variety of conditions. The aim of this study is to evaluate the effects of oral ingestion of CS and Lingzhi extracts of a period of 28 days on cardiopulmonary fitness and cognitive functioning in young, healthy physical education students.

Condition Intervention
Physical Fitness
Executive Function
Dietary Supplement: Cordyceps Sinensis (CS) and Lingzhi
Dietary Supplement: Tea and Flour

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider)
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Hillel Yaffe Medical Center:

Primary Outcome Measures:
  • Improvement in Cardiopulmonary Fitness after Ingestion of CS and Lingzhi Extracts [ Time Frame: 28 days ]
    Before and after 28-day ingestion of CS and Lingzhi extracts, subjects will undergo a graded exercise test on a treadmill and results will be compared.

Other Outcome Measures:
  • Effect of CS and Lingzhi on Cognitive Functioning [ Time Frame: 28 days ]
    Before and after 28-day ingestion of CS and Lingzhi the subjects undergo computerized cognitive tests and results will be compared.

Estimated Enrollment: 100
Study Start Date: December 2012
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: CS and Lingzhi
CS liquid (each dosage is a bottle of liquid containing 30 ml: comprising 75% of CS, 6% Lingzhi, 6% shitake, 5% bamboo shoot, 2% honey, 0.1% potassium sorbet and 5.9% pure water) and Lingzhi capsule (each capsule contains 620mg of: 52.42% Lingzhi, 28.23% CS, and 19.35% soy gel ) ; one quarter bottle of CS to be ingested twice a day, and the Lingzhi capsule to be taken once a day, both for a period of 28 days.
Dietary Supplement: Cordyceps Sinensis (CS) and Lingzhi
Placebo Comparator: Placebo
Liquid tea ingested twice a day and flour-filled capsules ingested once a day over a period of 28 days
Dietary Supplement: Tea and Flour


Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Physical education students

Exclusion Criteria:

  • All others
  Contacts and Locations
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Please refer to this study by its identifier: NCT01718548

Wingate Institute Not yet recruiting
Netanya, Israel
Contact: Sharon Tsuk, PhD    09-8639235   
Principal Investigator: Sharon Tsuk, PhD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
  More Information

Responsible Party: Hillel Yaffe Medical Center Identifier: NCT01718548     History of Changes
Other Study ID Numbers: 0062-12-HYMC
Study First Received: October 29, 2012
Last Updated: October 29, 2012 processed this record on May 25, 2017