The Effects of Puberty and Weight on Sugar Metabolism in Children
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|ClinicalTrials.gov Identifier: NCT01718080|
Recruitment Status : Completed
First Posted : October 31, 2012
Last Update Posted : April 24, 2017
Our goal is to investigate how hormones that control blood sugar, hunger, and stomach emptying change with puberty and being overweight. These substances change with a meal.
- For this, we need to compare lean and overweight children.
- We need to study them before and during puberty.
- All children in the study will be tested before and after a liquid meal.
|Condition or disease|
|Overweight Leanness Adolescent|
|Study Type :||Observational|
|Actual Enrollment :||83 participants|
|Official Title:||The Role of Puberty and Insulin Resistance in the Development of Hyperglucagonemia|
|Actual Study Start Date :||October 2012|
|Actual Primary Completion Date :||January 2015|
|Actual Study Completion Date :||June 2015|
Healthy lean children before puberty
Otherwise healthy overweight children before puberty
Healthy lean adolescents in mid to late puberty
Otherwise healthy overweight adolescents in mid to late puberty
- Overweight and Lean Children Sugar Metabolism Before and During Puberty [ Time Frame: 4 hours ]Too much weight gain can cause changes in the substances that control blood sugar and hunger in the body. Scientists need to compare these substances in lean and overweight children before and during puberty. These substances can be measured before and after a meal in the blood and in the urine. The way your stomach moves food can change your sugar levels. We want to understand how diabetes develops by studying these things. This can help find better ways to prevent and treat diabetes.
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01718080
|United States, Texas|
|Baylor College of Medicine|
|Houston, Texas, United States, 77030|
|Principal Investigator:||Luisa M. Rodriguez, MD||Baylor College of Medicine|