Measuring Eating, Activity and Strength: Understanding the Response -Using Protein (MEASUR-UP)
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|ClinicalTrials.gov Identifier: NCT01715753|
Recruitment Status : Completed
First Posted : October 29, 2012
Last Update Posted : March 30, 2018
|Condition or disease||Intervention/treatment||Phase|
|Weight Loss||Dietary Supplement: Protein supplementation Behavioral: Diet counseling and group education lessons||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||71 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Does Enhanced Protein Intake Preserve Function and Lean Muscle Mass During Weight Reduction in Frail, Obese Older Adults?|
|Study Start Date :||September 2012|
|Actual Primary Completion Date :||December 2014|
|Actual Study Completion Date :||December 2014|
Active Comparator: Weight Loss Control
Diet counseling and group education lessons. Subjects follow a calorie-reduction diet for a weight loss of ≥10%.
Behavioral: Diet counseling and group education lessons
Individual and group diet counseling to achieve a >10% weight loss
Experimental: Weight Loss-High Protein
Protein supplementation. Subjects follow a calorie-reduction diet for a weight loss of ≥10%, with a high proportion of protein, including substantial amounts of supplemental protein provided as lean beef. Intakes of > 30g of high quality protein will be achieved three times a day by subjects in this group, with all or predominantly all from animal source and 60-70% of animal protein from beef.
Dietary Supplement: Protein supplementation
> 30g of high quality protein will be achieved three times a day by subjects in this group, with all or predominantly all from animal source and 60-70% of animal protein from beef.
- Change in Short Physical Performance Battery (SPPB) [ Time Frame: Baseline to 3 to 6 months ]short physical performance battery
- Change in lean body mass [ Time Frame: Baseline to 3 and 6 months ]Bodpod
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01715753
|United States, North Carolina|
|Duke University Medical Center|
|Durham, North Carolina, United States, 27710|
|Principal Investigator:||Connie W Bales, PhD, RD||Duke University|