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Availability of Poor Quality Embryos (Availability)

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ClinicalTrials.gov Identifier: NCT01715545
Recruitment Status : Completed
First Posted : October 29, 2012
Last Update Posted : October 29, 2012
Sponsor:
Information provided by (Responsible Party):
Yang Jie, The Second Affiliated Hospital of Kunming Medical University

Brief Summary:
The purpose of this study is to explore a method to identify the viability of day-3 poor quality embryos

Condition or disease
Infertility

Detailed Description:
Day-3 poor quality embryos are related to significant lower clinical pregnancy,so freezing numerous poor quality embryos are clinical impractical. To ensure the successful pregnancy and to enhance the availability of the poor quality embryos, day-3 poor quality embryos are further cultured to different developmental stage and then cryopreserved. The viability of these embryos are tested in frozen-thawed transfer.

Study Type : Observational
Actual Enrollment : 481 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Availability of Poor Quality Embryos in Frozen-thawed Embryo Transfer Cycles
Study Start Date : January 2011
Actual Primary Completion Date : April 2012
Actual Study Completion Date : October 2012

Group/Cohort
day-3 poor quality embryos
developmental stage
day3 poor quality embryos day4 morular day-5/6 blastocyst



Primary Outcome Measures :
  1. pregnancy rate [ Time Frame: 5 weeks ]


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Ages Eligible for Study:   20 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
unfertile women
Criteria

Inclusion Criteria:

  • unfertile women

Exclusion Criteria:

  • women older than 40 years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01715545


Locations
China, Yunnan
The Second Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, China, 650101
Sponsors and Collaborators
The Second Affiliated Hospital of Kunming Medical University
Investigators
Principal Investigator: Jie Yang The Second Affiliated Hospital of Kunming Medical University

Publications:
(1) Lu LI, Xiao-xi SUN, Jun-ling CHEN, et al. Analysis of Factors Influencing Pregnancy Rate in Frozen-thawed Embryo Transfer. Journal of Reproduction and Contraception (2004) 15 (4):239-244

Responsible Party: Yang Jie, The Second Affiliated Hospital of Kunming Medical University
ClinicalTrials.gov Identifier: NCT01715545     History of Changes
Other Study ID Numbers: 200601YJ
First Posted: October 29, 2012    Key Record Dates
Last Update Posted: October 29, 2012
Last Verified: October 2012

Keywords provided by Yang Jie, The Second Affiliated Hospital of Kunming Medical University:
day-3 poor quality embryo
vitrification
clinical outcome

Additional relevant MeSH terms:
Infertility
Genital Diseases, Male
Genital Diseases, Female