Autonomic Nervous System Activity and Oculocardiac Reflex.
Recruitment status was Recruiting
Pulling the eyeball during ophthalmic surgery provokes decrease in heart rate. This phenomenon is called oculocardiac reflex. In some patients asystole may occur. Other cardiac features of this reflex include hypotension, dysrhythmias, atrioventricular block. These cardiovascular disturbances may lead to decreased perfusion and ischemia of vital organs. Patients with existing cardiovascular disease are in risk of complications. Cardiovascular system is mainly innervated with autonomic nervous system (ANS). Sympathetic/parasympathetic activity may be determined by Heart Rate Variability (HRV). HRV analysis based on short 5 minutes electrocardiography has been found useful for prediction of hypotension and bradycardia during induction of general anaesthesia and during spinal block. The aim of this study is to verify whether it is possible to predict oculocardiac reflex with the use of HRV analysis for ANS activity assessment, measured prior to the ophthalmic surgery.
Bradycardia During Pulling of Eyeball
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Prediction of Oculocardiac Reflex in Relationship to Autonomic Nervous System Activity, Mesured With the Use of ECG HRV Analysis.|
- oculocardiac reflex occurence in relation to autonomic system activity [ Time Frame: up to 2 years ] [ Designated as safety issue: No ]
|Study Start Date:||April 2009|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01714362
|Medical University of Gdansk||Recruiting|
|Gdansk, Poland, 80-211|
|Contact: Magdalena A. Wujtewicz, MD., PhD 48583493281 firstname.lastname@example.org|