Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries
|ClinicalTrials.gov Identifier: NCT01712698|
Recruitment Status : Withdrawn
First Posted : October 23, 2012
Last Update Posted : January 24, 2018
|Condition or disease|
|Cervical Spinal Cord Injury|
Diffusion tensor imaging (DTI) parameters will correlate with severity of spinal cord injury in SCI patients as seen in rodent models. We will test whether the quantitative decrease in axial (λ║) diffusivity (a biomarker of axonal injury), will predict long-term functional outcomes for patients with a SCI.
Specific Aim: To examine patients after an acute SCI using DTI and to correlate the extent of acute decrease in λ║ with the presenting ASIA motor score and long-term functional outcome of the patient.
|Study Type :||Observational|
|Actual Enrollment :||0 participants|
|Official Title:||Diffusion Tensor MRI to Assess Subacute Functional Outcomes in Patients With Acute Cervical Spinal Cord Injuries|
|Study Start Date :||January 2014|
|Actual Primary Completion Date :||January 2016|
|Actual Study Completion Date :||January 2016|
Cervical spinal cord injury
Those patients with an acute cervical spinal cord injury evaluated with DTI MRI
- Change in AISA score [ Time Frame: 24 months ]Patients will be followed for the duration of their hospital stay with clinical follow-up out to 2 years. ASIA scores will be correlated with admission DTI findings(Axial Diffusivity).
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01712698
|United States, Missouri|
|Washington University, School of Medicine|
|Saint Louis, Missouri, United States, 63110|