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The Effects of Glucomannan on Weight Loss

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ClinicalTrials.gov Identifier: NCT01709955
Recruitment Status : Completed
First Posted : October 18, 2012
Last Update Posted : October 18, 2012
Sponsor:
Information provided by (Responsible Party):
Denise Holtzman MS DC, Northeast College of Health Sciences

Study Description
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Brief Summary:
The purpose of this study is to determine if the herb, Glucomannan, is an effective non-pharmacological appetite suppressant for overweight or Class I obese patients. The study design will not include any other lifestyle changes which enhance weight loss in order to completely isolate the effects of Glucomannan as a non-pharmacological appetite suppressant.

Condition or disease Intervention/treatment Phase
Obesity Dietary Supplement: Glucomannan Other: Placebo Phase 1

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 43 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Study Start Date : February 2011
Actual Primary Completion Date : July 2011
Actual Study Completion Date : July 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Weight Control

Arms and Interventions
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Arm Intervention/treatment
Experimental: Gucomannan Dietary Supplement: Glucomannan
750 MG of Glucomannan in capsule form
Placebo Comparator: Placebo pill Other: Placebo
750 mg of Cellulose powder in a capsule form


Outcome Measures
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Primary Outcome Measures :
  1. Weight Loss [ Time Frame: 30 Days ]

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:Subjects will be recruited based upon the category of them wanting to lose 50 pounds.

Subjects must be able to swallow the capsule whole with water.

Exclusion Criteria:

  1. Self-reported use of prescription medication other than hormonal birth control (such as medication for diabetes, hypertension hypothyroidism, heart disease, cancer, etc.)
  2. Pregnancy
  3. Age younger than 21 or older than 60 years of age.
  4. Screening for hypertension during the first laboratory visit that reveals a systole greater than 120 and a diastole greater than 90.
  5. BMI calculations based upon height and weight measurements at the first laboratory visit that reveal a BMI less than 25 or greater than 35.
  6. Self-reported iron-deficiency anemia, osteoporosis, and hypoglycemia.
Contacts and Locations
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No Contacts or Locations Provided
More Information
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Responsible Party: Denise Holtzman MS DC, Associate professor, Northeast College of Health Sciences
ClinicalTrials.gov Identifier: NCT01709955    
Other Study ID Numbers: 10-13
First Posted: October 18, 2012    Key Record Dates
Last Update Posted: October 18, 2012
Last Verified: October 2012
Keywords provided by Denise Holtzman MS DC, Northeast College of Health Sciences:
Obesity
Overweight
Glucomannan
Additional relevant MeSH terms:
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Obesity
Overnutrition
Nutrition Disorders
Overweight
 Body Weight
(1-6)-alpha-glucomannan
Cathartics
Gastrointestinal Agents