Musical Dual Task Training to Improve Attention Control for Dementia
Recruitment status was Recruiting
The purpose of this project is to determine if the Musical Dual Task Training program improves attention control that influences measures of gait performances under dual tasking, balance, fear of falling, and behavioral disturbance in patients with mild to moderate dementia. This Musical Dual Task Training protocol is structured with musical content and patients are required to do musical tasks including singing and playing instruments contingent on visual or auditory cues while walking. This paradigm is designed to include music making because it involves great demands on attention and memory that might elicit experience-dependent plasticity in the brain. Musical Dual Task Training is proposed to strengthen brain networking for attention control that consequently may improve the gait performances in patients with dementia, as indicated by reducing dual task cost on gait.
Behavioral: Musical Dual Task Training
Behavioral: Walking and Talking
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||The Effects of Musical Dual Task Training on Attention Control and Associated Gait Stability of Patients With Mild to Moderate Dementia|
- Change from Baseline on the Trail Making Test at 2 months [ Time Frame: Baseline and at 2 months ] [ Designated as safety issue: No ]Trail Making Test Part A requires the participants to draw lines to connect a set of 25 circles as fast as possible following the sequential order of numbers (1,2,3…25) while still maintaining accuracy. Trail Making Test Part B is in a same format, but participants are required to alternates between numbers and letters (1, A, 2, B, etc.). The circles in Part B include both numbers (1 - 13) and letters (A - L). Results for both Part A and Part B are reported as the number of seconds required to complete the task. Higher scores indicate greater impairment.
- Change from Baseline on Walking Speed during Dual tasking at 2 Months [ Time Frame: Baseline and at 2 months ] [ Designated as safety issue: No ]
- Change from Baseline on the Timed Up-and-Go test at 2 Months [ Time Frame: Baseline and 2 months ] [ Designated as safety issue: No ]
- Change from Baseline on the 7-item Short Falls Efficacy Scale International at 2 Months [ Time Frame: Baseline and at 2 months ] [ Designated as safety issue: No ]
- Change from Baseline on the Cohen-Mansfield Agitation Inventory scale at 2 months [ Time Frame: Baseline and at 2 months ] [ Designated as safety issue: No ]
- Change from Baseline on Stride Lengths during Dual Tasking at 2 Months [ Time Frame: Baseline and at 2 months ] [ Designated as safety issue: No ]
|Study Start Date:||October 2012|
|Estimated Study Completion Date:||October 2013|
|Estimated Primary Completion Date:||October 2013 (Final data collection date for primary outcome measure)|
Experimental: Musical Dual Task Training
60 minute individual session once a week across 2 months for a total of 8 sessions.Each session will be led by a qualified music therapist. Within the Musical Dual Task Training session, participant will be asked to sing familiar songs, play simple percussive musical instruments such as paddle drums and shakers, sing while walking, and play instruments while walking.
|Behavioral: Musical Dual Task Training|
Active Comparator: Walking and Talking
60 minute individual session once a week across 2 months for a total of 8 sessions.Each session will be led by a qualified music therapist. Within the walking and talking session, participant will be asked to read a newspaper article prior to a walk and have a conversation with the music therapist based on the content of the news while walking.
|Behavioral: Walking and Talking|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01709188
|Contact: Yu-Cheng Pei, MD, PhD||886-3-3281200 ext firstname.lastname@example.org|
|Contact: Yu-Ling Chen, MA, MMEemail@example.com|
|Chang Gung Medical Foundation||Recruiting|
|Taoyuan, Taiwan, 333|
|Contact: Yu-Cheng Pei, MD, PhD 886-3-3281200 ext 3846 firstname.lastname@example.org|
|Principal Investigator: Yu-Cheng Pei, MD, PhD|
|Principal Investigator:||Yu-Cheng Pei, MD, PhD||Chang Gung Medical Foundation|