The MURDOCK Study Registry and Biorepository Horizon 1.5 (MURDOCK)
This study is currently recruiting participants.
(see Contacts and Locations)
Verified August 2016 by Duke University
Sponsor:
Duke University
Information provided by (Responsible Party):
Duke University
ClinicalTrials.gov Identifier:
NCT01708408
First received: October 15, 2012
Last updated: August 1, 2016
Last verified: August 2016
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Purpose
The MURDOCK Study Community Registry and Biorepository (Horizon 1.5) aims to create a large-scale community registry and biorepository that can be used as a vehicle for future health services, epidemiologic, clinical trials and other omics-related research.
| Condition | Intervention |
|---|---|
|
Chronic Disease Healthy Volunteers |
Genetic: Biomarker studies |
| Study Type: | Observational |
| Study Design: | Time Perspective: Prospective |
| Official Title: | Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis The MURDOCK Study Registry and Biorepository Horizon 1.5 |
Resource links provided by NLM:
Further study details as provided by Duke University:
Primary Outcome Measures:
- The MURDOCK Study Registry and Biorepository Horizon 1.5 [ Time Frame: Upto 119 months ] [ Designated as safety issue: No ]To provide information for large-scale epidemiologic and clinical translational research and the research infrastructure to identify specific phenotypes and outcomes to improve medicine
Biospecimen Retention: Samples With DNA
Blood, 50 mL (whole blood, plasma, serum, buffy coat, PAXgene); Urine, 36 mL
| Estimated Enrollment: | 50000 |
| Study Start Date: | February 2009 |
| Estimated Study Completion Date: | December 2018 |
| Estimated Primary Completion Date: | December 2018 (Final data collection date for primary outcome measure) |
| Groups/Cohorts | Assigned Interventions |
|---|---|
| community | Genetic: Biomarker studies |
Detailed Description:
The MURDOCK Study Community Registry and Biorepository's activities include enrolling approximately 50,000 participants who live in Cabarrus County and/or Kannapolis, North Carolina. Participants must consent to (1) use of the data provided by the participant through completion of the Participant Registry Questionnaire for epidemiologic population characterization, (2) annual contact to update their MURDOCK Horizon 1.5 database record, (3) release of their medical information, including but not limited to demographic information, problem lists, medications, social and family history, and results of laboratory and other testing modalities from pre-existing paper or electronic health records or electronic health records that may become available in the future, (4) provision of a blood and urine sample, and (5) contact up to four times/year to request participation in additional research studies.
Eligibility| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Study Population
The Community Registry and Biorepository is designed to create a community registry and biorepository populated by approximately 50,000 residents of Cabarrus County and/or the city of Kannapolis in North Carolina.
Criteria
Inclusion Criteria:
- A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) for 6 or more months of the year
- At least 18 years of age
- Able to understand and give written informed consent, or have a legal guardian or caregiver present to give informed consent by proxy (assent from a participant between ages 12-18 will be obtained when their parent or legal guardian consents on their behalf).
- Willing and able to participate in all 5 components of the registry and biorepository as described above in Section III
Exclusion Criteria:
1. There are no exclusions to participation if all inclusion criteria have been met.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01708408
Please refer to this study by its ClinicalTrials.gov identifier: NCT01708408
Contacts
| Contact: Leah Bouk | 704-250-5856 | leah.bouk@duke.edu | |
| Contact: Perla Nunes | 704-250-5858 | perla.nunes@duke.edu |
Locations
| United States, North Carolina | |
| Duke Translational Medicine Institute-MURDOCK Study | Recruiting |
| Kannapolis, North Carolina, United States, 28081 | |
| Contact: Leah Bouk 704-250-5861 leah.bouk@duke.edu | |
| Contact: Perla Nunes 704-250-5858 perla.nunes@duke.edu | |
| Principal Investigator: L. Kristin Newby, MD, MHS | |
Sponsors and Collaborators
Duke University
Investigators
| Principal Investigator: | Robert M Califf, MD | Duke University |
More Information
Additional Information:
Publications:
| Responsible Party: | Duke University |
| ClinicalTrials.gov Identifier: | NCT01708408 History of Changes |
| Other Study ID Numbers: | Pro00011196 |
| Study First Received: | October 15, 2012 |
| Last Updated: | August 1, 2016 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by Duke University:
|
biorepository biobank registry community biospecimens volunteers |
chronic disease longitudinal blood electronic health records follow-up |
Additional relevant MeSH terms:
|
Chronic Disease Disease Attributes Pathologic Processes |
ClinicalTrials.gov processed this record on September 26, 2016