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The MURDOCK Study Registry and Biorepository Horizon 1.5 (MURDOCK)

This study is currently recruiting participants.
See Contacts and Locations
Verified February 2017 by Duke University
Information provided by (Responsible Party):
Duke University Identifier:
First received: October 15, 2012
Last updated: February 6, 2017
Last verified: February 2017
The MURDOCK Study Community Registry and Biorepository (Horizon 1.5) aims to create a large-scale community registry and biorepository that can be used as a vehicle for future health services, epidemiologic, clinical trials and other omics-related research.

Condition Intervention
Chronic Disease Healthy Volunteers Genetic: Biomarker studies

Study Type: Observational
Study Design: Observational Model: Other
Time Perspective: Prospective
Official Title: Measurement to Understand Reclassification of Disease of Cabarrus/Kannapolis The MURDOCK Study Registry and Biorepository Horizon 1.5

Further study details as provided by Duke University:

Primary Outcome Measures:
  • The MURDOCK Study Registry and Biorepository Horizon 1.5 [ Time Frame: Upto 119 months ]
    To provide information for large-scale epidemiologic and clinical translational research and the research infrastructure to identify specific phenotypes and outcomes to improve medicine

Biospecimen Retention:   Samples With DNA
Blood, 50 mL (whole blood, plasma, serum, buffy coat, PAXgene); Urine, 36 mL

Estimated Enrollment: 50000
Study Start Date: February 2009
Estimated Study Completion Date: December 2018
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
community Genetic: Biomarker studies

Detailed Description:
The MURDOCK Study Community Registry and Biorepository's activities include enrolling approximately 50,000 participants who live in Cabarrus County and/or Kannapolis, North Carolina. Participants must consent to (1) use of the data provided by the participant through completion of the Participant Registry Questionnaire for epidemiologic population characterization, (2) annual contact to update their MURDOCK Horizon 1.5 database record, (3) release of their medical information, including but not limited to demographic information, problem lists, medications, social and family history, and results of laboratory and other testing modalities from pre-existing paper or electronic health records or electronic health records that may become available in the future, (4) provision of a blood and urine sample, and (5) contact up to four times/year to request participation in additional research studies.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
The Community Registry and Biorepository is designed to create a community registry and biorepository populated by approximately 50,000 residents of Cabarrus County and/or the city of Kannapolis in North Carolina.

Inclusion Criteria:

  1. A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) for 6 or more months of the year
  2. At least 18 years of age
  3. Able to understand and give written informed consent, or have a legal guardian or caregiver present to give informed consent by proxy (assent from a participant between ages 12-18 will be obtained when their parent or legal guardian consents on their behalf).
  4. Willing and able to participate in all 5 components of the registry and biorepository as described above in Section III

Exclusion Criteria:

1. There are no exclusions to participation if all inclusion criteria have been met.

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01708408

Contact: Leah Bouk 704-250-5856
Contact: Perla Nunes 704-250-5858

United States, North Carolina
Duke Translational Medicine Institute-MURDOCK Study Recruiting
Kannapolis, North Carolina, United States, 28081
Contact: Leah Bouk    704-250-5861   
Contact: Perla Nunes    704-250-5858   
Principal Investigator: L. Kristin Newby, MD, MHS         
Sponsors and Collaborators
Duke University
Principal Investigator: Robert M Califf, MD Duke University
  More Information

Additional Information:
Responsible Party: Duke University Identifier: NCT01708408     History of Changes
Other Study ID Numbers: Pro00011196
Study First Received: October 15, 2012
Last Updated: February 6, 2017

Keywords provided by Duke University:
chronic disease
electronic health records

Additional relevant MeSH terms:
Chronic Disease
Disease Attributes
Pathologic Processes processed this record on September 21, 2017