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Surgery for Intravenous Leiomyomatosis (SIVL)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01707862
Recruitment Status : Completed
First Posted : October 16, 2012
Last Update Posted : October 16, 2012
Information provided by (Responsible Party):
Li Yang, General Hospital of Beijing PLA Military Region

Brief Summary:
Intravenous leiomyomatosis (IVL) with intracardiac extension is a rare benign smooth muscle tumor. Reviewing literature, intracardiac extension of the IVL has been reported in at least 70 cases. Most are individual case reports. Surgical experience is not much. However, different opinion of surgical strategies remain controversial. The purpose of this report is to describe our experience of surgical management for the IVL with intracardiac extension.

Condition or disease

Detailed Description:
All patients underwent surgical management. Clinical data were obtained from medical reports. Following-up was made through email and telephone.

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Study Type : Observational
Actual Enrollment : 6 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Surgical Management of Intravenous Leiomyomatosis With Intracardiac Extension: Our Experience and Outcomes
Study Start Date : March 1997
Actual Primary Completion Date : April 2012
Actual Study Completion Date : October 2012

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
From March 1997 to June 2011, 6 women patients were admitted to our hospital with intravenous leiomyomatosis with intracardiac extension.

Inclusion Criteria:

  • Age more than 18 years.
  • Tumor markers were all within normal limits.
  • Patients underwent surgical management.
  • Patients were followed-up for more than 12 months.

Exclusion Criteria:

-Tumor markers were all within abnormal limits

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01707862

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Institute of Cardiovascular Disease
Beijing, China
Sponsors and Collaborators
Li Yang
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Principal Investigator: Genetal Hospital Beijing Military Region, First class Institute of Cardiovascular Disease

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Responsible Party: Li Yang, Doctor, General Hospital of Beijing PLA Military Region Identifier: NCT01707862    
Other Study ID Numbers: GHBeijing-20121012
First Posted: October 16, 2012    Key Record Dates
Last Update Posted: October 16, 2012
Last Verified: October 2012
Keywords provided by Li Yang, General Hospital of Beijing PLA Military Region:
Intravenous leiomyomatosis
Smooth muscle tumor
Additional relevant MeSH terms:
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Neoplasms, Muscle Tissue
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type