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The Effects of Low- and High-intensity Resistance Exercise on Force-velocity Characteristics in Older Adults

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01707017
First Posted: October 15, 2012
Last Update Posted: February 20, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Universitaire Ziekenhuizen Leuven
  Purpose
The purpose of this study is to compare the impact of high- and low-intensity resistance exercise on force-velocity characteristics, muscle mass and inflammatory processes in older adults. As all training protocols are designed to end with maximal effort, effects are expected to be similar between groups.

Condition Intervention
Effects of Strength Training in Older Adults Other: Strength training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)

Further study details as provided by Universitaire Ziekenhuizen Leuven:

Primary Outcome Measures:
  • Change in force-velocity characteristics of knee extensors [ Time Frame: Baseline, 12weeks, 6 months ]

Other Outcome Measures:
  • Change in muscle volume [ Time Frame: Baseline, 12weeks, 6 months ]
  • Change in maximal strength (one repetition maximum) [ Time Frame: Baseline, 4weeks, 8weeks, 12weeks, 6 months ]
    Strength is measured as the maximum weight on the training equipment that can be lifted only one time (= one repetition maximum).

  • Change in motivation [ Time Frame: Baseline, every week for 12 weeks, 6 months ]
  • Change in physical activity [ Time Frame: Baseline, 12weeks, 6 months ]
  • Change in inflammatory markers in blood [ Time Frame: Baseline, 12weeks, 6 months ]

Enrollment: 56
Study Start Date: January 2012
Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: High-load strength training Other: Strength training
Active Comparator: Low-load strength training Other: Strength training
Active Comparator: Low-load + moderate-load strength training Other: Strength training

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • age 60 to 80 years

Exclusion Criteria:

  • Knee or hip prothesis
  • Systematic training
  • Cardiovascular disease
  • Acute lower back pain
  • Dementia
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01707017


Locations
Belgium
Faculty of Kinesiology and Rehabilitation Sciences
Leuven, Belgium, 3001
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven
  More Information

Responsible Party: Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT01707017     History of Changes
Other Study ID Numbers: S53709
First Submitted: October 2, 2012
First Posted: October 15, 2012
Last Update Posted: February 20, 2013
Last Verified: November 2011