Esophageal Manometry and Impedance Study in Obese Patients Before and During Anesthesia

This study has been withdrawn prior to enrollment.
Information provided by (Responsible Party):
Alex de Leon, Örebro University, Sweden Identifier:
First received: October 8, 2012
Last updated: November 4, 2014
Last verified: November 2014
The purpose of this study is to evaluate the effects of anesthesia on the esophageal body in obese patients before and during anesthesia.

Condition Intervention
Device: Manometry and Impedance analysis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation of Esophageal Pressures and Reflux in Obese Patients Before and During Anesthesia Using High-resolution Solid-state Manometry

Resource links provided by NLM:

Further study details as provided by Örebro University, Sweden:

Primary Outcome Measures:
  • Esophageal pressures after laparoscopic gastric by pass [ Time Frame: 2 years after surgery ] [ Designated as safety issue: No ]

Enrollment: 0
Study Start Date: October 2012
Groups/Cohorts Assigned Interventions
Obese patients Device: Manometry and Impedance analysis

Detailed Description:

Obesity is an increasing heath problem in western countries and is associated with increased risks during anesthesia.

Using high-resolution solid-state manometry the investigators aim to study esophageal pressures and measure the incidence of regurgitation of gastric contents during anesthesia induction in obese patients. The investigators aim to include 16 obese patients, with BMI > 35, undergoing laparoscopic gastric by-pass.


Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Obese patients

Inclusion Criteria:

  • Male and female patients
  • aged 18-60 years
  • BMI>35
  • ASA classification I-III

Exclusion Criteria:

  • Use of drugs that interfere with esophageal motility
  • Gastro-esophageal reflux disease
  Contacts and Locations
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Please refer to this study by its identifier: NCT01703897

Department of Anesthesiology and Intensive care, University Hospital of Örebro
Örebro, Sweden, 70162
Sponsors and Collaborators
Örebro University, Sweden
  More Information

No publications provided

Responsible Party: Alex de Leon, MD, PhD, Örebro University, Sweden Identifier: NCT01703897     History of Changes
Other Study ID Numbers: Linde-Imped
Study First Received: October 8, 2012
Last Updated: November 4, 2014
Health Authority: Sweden: Regional Ethical Review Board

Keywords provided by Örebro University, Sweden:
gastric by-pass surgery processed this record on December 01, 2015