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Complementary and Alternative Care in Multiple Sclerosis (CAM Care in MS)

This study is currently recruiting participants.
See Contacts and Locations
Verified July 2017 by Laurie Mischley, Bastyr University
Information provided by (Responsible Party):
Laurie Mischley, Bastyr University Identifier:
First received: October 3, 2012
Last updated: July 26, 2017
Last verified: July 2017
This is a prospective, observational study designed to describe disease progression, symptom change, quality of life, diet and lifestyle habits, and frequency of adverse events among patients with multiple sclerosis (MS) who use complementary and alternative medicine (CAM). In addition to describing the patterns of CAM use, this study will also identify and describe the positive deviants, those individuals with the highest quality of life and least amount of disease activity. Positive deviants will be compared to controls in order to describe medication, diet, and lifestyle patterns associated with a lack of MS disease progression and high quality of life.

Multiple Sclerosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Complementary and Alternative Medicine (CAM) in Multiple Sclerosis. A Prospective Observational Study of a CAM-using Cohort

Resource links provided by NLM:

Further study details as provided by Laurie Mischley, Bastyr University:

Primary Outcome Measures:
  • "CAM Therapies" survey [ Time Frame: 5 years ]
    This survey has been developed to identify the complementary and alternative therapies most commonly used by individuals with MS. Results will be reported with descriptive statistics.

Secondary Outcome Measures:
  • Modified Expanded Disability Severity Score (EDSS) [ Time Frame: 5 years ]
    The EDSS will be used to capture disease severity and rates of progression in this cohort.

Other Outcome Measures:
  • PROMIS: Global Health [ Time Frame: 5 years ]
    This outcome measure will be used to assess general health and well-being in this CAM using cohort.

Estimated Enrollment: 1000
Study Start Date: June 2012
Estimated Study Completion Date: June 2040
Estimated Primary Completion Date: June 2040 (Final data collection date for primary outcome measure)
Individuals with MS


Ages Eligible for Study:   18 Years to 100 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Any individual with multiple sclerosis is invited to participate.

Inclusion Criteria:

  • Diagnosis of multiple sclerosis (including relapsing remitting MS, secondary progressive MS, primary progressive MS, clinically isolated syndromes (CIS), radiologically-isolated syndromes (RIS), possible MS, or probable MS.
  • Age 18-100

Exclusion Criteria:

  • Inability to read/write in English
  • Inability or unwillingness to complete surveys every six (6) months. (~ 90 min)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01703429

United States, Washington
Bastyr University Clinical Research Center Recruiting
Kenmore, Washington, United States, 98028
Contact: Laurie K Mischley, ND, MPH    425-602-3306   
Principal Investigator: Laurie K Mischley, ND, MPH         
Sponsors and Collaborators
Bastyr University
Principal Investigator: Laurie K Mischley, ND, MPH Bastyr University
  More Information

Additional Information:
Responsible Party: Laurie Mischley, Clinical Research Assistant Professor, Bastyr University Identifier: NCT01703429     History of Changes
Other Study ID Numbers: BU-11A-1296
Study First Received: October 3, 2012
Last Updated: July 26, 2017

Keywords provided by Laurie Mischley, Bastyr University:
Multiple Sclerosis
Complementary and Alternative

Additional relevant MeSH terms:
Multiple Sclerosis
Pathologic Processes
Demyelinating Autoimmune Diseases, CNS
Autoimmune Diseases of the Nervous System
Nervous System Diseases
Demyelinating Diseases
Autoimmune Diseases
Immune System Diseases processed this record on September 19, 2017