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Preexpanded Perforator Flaps in Children

This study has been completed.
Information provided by (Responsible Party):
Emre Hocaoglu, Istanbul University Identifier:
First received: October 1, 2012
Last updated: October 2, 2012
Last verified: October 2012
Contractures and broad scars of the axilla, anterior chest wall and neck have detrimental effects on functional, physical and psychological development of children. Perforator flaps have already been shown to be reliable options for the reconstruction of contractures but there have been no reports demonstrating the value of preexpanded perforator flaps of dorsolateral trunk region in treatment of extensive contractures and scars of pediatric patients. The purpose of this study is to demonstrate these techniques by a case series formed of pediatric patients with broad scars and contractures of anterior chest wall, axilla, neck and breasts. Seven pediatric patients (mean age, 11,6 years) who were treated by preexpanded perforator flaps are presented. By this means, clinical experience on intercostal artery perforator (ICAP) flap, thoracodorsal artery perforator (TDAP) flap, circumflex scapular artery perforator (CSAP) flap and lumbar artery perforator flap was shared. Flaps as large as 20,5x10,5 cm in size could be successfully transferred in pediatric patients. Broad scar tissues were resurfaced with broad flaps carrying similar characteristics with the uninjured anterior chest wall and neck skin in six of our patients. In one patient with partial necrosis, full thickness skin graft was used for the residual defect. The mean duration of postoperative (after flap transfer) follow-ups was 17,2 months. The preexpanded TDAP, ICAP and CSAP flaps are revealed to be useful reconstructive options for the treatment of scars and contractures of anterior chest wall, axilla, neck and breast in pediatric patients.

Condition Intervention
Contractures Scars Procedure: new technical intervention

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Preexpanded Perforator Flaps in Pediatric Patients

Resource links provided by NLM:

Further study details as provided by Emre Hocaoglu, Istanbul University:

Primary Outcome Measures:
  • Range of motion of the particular joint [ Time Frame: at least three months after flap tarnsfer ]
    Disruption of the contracture band and releasing the contracture of a particular joint results in achievement of the healthy range of motion of that joint.

Secondary Outcome Measures:
  • Replaced tissue dimensions [ Time Frame: at least three months after the operation ]
    Transferred flap sizes will be documented. It is a way of demonstrating the amount of replaced scar tissue and exhibiting the success of the technique.

Other Outcome Measures:
  • Developement of related anatomic structures [ Time Frame: at least a year after flap transfer ]
    Resurfacing the broad scar tissue and releasing the contracture leads to normal developement of the relevant extremity, chest, neck, breast and posture of the patient, thus, providing the healthy developement of the child.

Enrollment: 7
Study Start Date: September 2012
Study Completion Date: September 2012
Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: new technical intervention
''new technical intervention'' represents the surgical procedure which is applied for the patients assigned to this group because of their certain characteristics. Namely, pediatric patients with broad axillary, anterior chest wall, mammary and neck scars are treated with this surgical approach.
Procedure: new technical intervention
Contractures and broad scars of the subjects are treated by this surgical intervention which is a reconstructive surgery that is performed by the transfer of preexpanded perforator flaps to the recipient sites of skin deficiency.
Other Name: reconstructive surgery by transfer of preexpanded perforator flaps


Ages Eligible for Study:   up to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • pediatric age group
  • broad scars and contractures

Exclusion Criteria:

  • age over 18 years
  • minimal scars and skin defects that could be treated by minor interventions
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Please refer to this study by its identifier: NCT01700595

Istanbul University, Istanbul Faculty of Medicine
Istanbul, Turkey, 34093
Sponsors and Collaborators
Istanbul University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Emre Hocaoglu, Specialist, M.D., Istanbul University Identifier: NCT01700595     History of Changes
Other Study ID Numbers: hocaoglupediatricperforator1
emrehocaoglu ( Registry Identifier: clinical trials )
Study First Received: October 1, 2012
Last Updated: October 2, 2012

Additional relevant MeSH terms:
Joint Diseases
Musculoskeletal Diseases
Muscular Diseases processed this record on August 21, 2017