Collection of Cerebrospinal Fluid in Healthy Children
The purpose of this study is to obtain cerebrospinal fluid from healthy children already undergoing a lumbar puncture procedure at New York Presbyterian Hospital, to act as healthy controls when compared to children with late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal neurodegenerative disease.
Late Infantile Neuronal Ceroid Lipofuscinosis
|Study Design:||Observational Model: Case-Only
Time Perspective: Cross-Sectional
|Official Title:||Collection of Cerebrospinal Fluid in Healthy Children|
- Cerebrospinal fluid (CSF) [ Time Frame: 1 time point (once) ] [ Designated as safety issue: No ]The primary study endpoint is the metabolic profiling of 32 samples of cerebrospinal fluid from healthy subjects, in comparison to 32 samples of CSF from children with LINCL, to determine whether there are biomarkers found in the cerebrospinal fluid that are associated with LINCL.
Biospecimen Retention: Samples Without DNA
5 mL of cerebrospinal fluid (CSF) will be collected in this study at one time point.
|Study Start Date:||December 2011|
|Estimated Study Completion Date:||December 2015|
|Estimated Primary Completion Date:||December 2015 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01698229
|United States, New York|
|Weill Cornell Medical College / New York Presbyterian Hospital|
|New York, New York, United States, 10065|
|Principal Investigator:||Ronald G Crystal, MD||Weill Medical College of Cornell University|