Is There a Relationship Between Previous Exposure to General Anesthesia and the Development of Alzheimer´s Disease? (DEMA)
The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2012 by University Hospital, Linkoeping.
Recruitment status was Recruiting
Information provided by (Responsible Party):
Anna-Karin Strand, MD, University Hospital, Linkoeping
First received: September 27, 2012
Last updated: September 28, 2012
Last verified: September 2012
The purpose of this study is to compare exposure to general anesthesia between cases with a diagnosis of Alzheimer´s disease and controls without diagnosis, through studies of medical records. The investigators wish to explore if there is a relationship between exposure to general anesthesia and the development of Alzheimer´s disease.
||Observational Model: Case Control
Time Perspective: Retrospective
||A Case-control Study of Exposure to General Anesthesia and a Diagnosis of Alzheimer´s Disease Later in Life.
Primary Outcome Measures:
- Exposure to general anesthesia [ Time Frame: Up to 20 years in retrospect ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Exposure to inhaled anesthetics [ Time Frame: Up to 20 years in retrospect ] [ Designated as safety issue: No ]
| Estimated Enrollment:
| Study Start Date:
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Cases from a regional Alzheimer´s disease record. Matched controls from the national population register.
- Clinical diagnosis of Alzheimer´s disease
- Previous exposure to anesthesia
- Inability to retrieve medical records
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01695889
|Linkoping, Sweden, 58185 |
University Hospital, Linkoeping
||Christina Eintrei, professor
||University Hospital Linkoping
No publications provided
||Anna-Karin Strand, MD, Specialist in Anaesthesiology and Intensive Care, University Hospital, Linkoeping
History of Changes
|Other Study ID Numbers:
|Study First Received:
||September 27, 2012
||September 28, 2012
||Sweden: Regional Ethical Review Board
Sweden: The National Board of Health and Welfare
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on February 26, 2015
Central Nervous System Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Nervous System Diseases