Neovascularization Patterns in Corneal Graft Rejection
Corneal transplantation is the most commonly performed human tissue transplant worldwide. Over 40,000 corneal transplants occur in the US each year. .
This study will determine specific corneal neovascularization (CN) patterns in human corneal allograft recipients to determine the characteristics that worsen the prognosis for graft survival. We will test the hypothesis that specific characteristics of CN are prognostic for corneal allograft rejection.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Neovascularization Patterns in Corneal Graft Rejection|
- Corneal graft rejection [ Time Frame: 0 to 2 years after transplant ]
|Study Start Date:||November 2007|
|Study Completion Date:||December 2016|
|Primary Completion Date:||December 2015 (Final data collection date for primary outcome measure)|
Subjects undergoing penetrating keratoplasty
Please refer to this study by its ClinicalTrials.gov identifier: NCT01695655
|United States, Michigan|
|Kellogg Eye Center|
|Ann Arbor, Michigan, United States, 48105|
|Principal Investigator:||Roni Shtein, MD, MS||University Of Michigam Kellogg Eye Center|