Intracoronary Imaging With NIRS-IVUS to Characterize Arterial Plaques (NIRS-IVUS)
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To characterize atherosclerotic coronary artery plaques using advanced intra-coronary imaging with a combined near-infrared spectroscopy and intravascular ultrasound catheter before and after percutaneous intervention
Condition or disease
Coronary Artery Disease
This study is being performed to characterize the composition and morphologic characteristics of atherosclerotic coronary artery plaques with intra-coronary near-infrared spectroscopy and intravascular ultrasound in patients undergoing percutaneous coronary intervention.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Coronary Artery Disease Patients
Subject is at > 18 years of age
Subject presents to the catheterization laboratory to undergo clinically-indicated, invasive coronary angiography
Subject is willing and able to provide informed written consent
Subject is found to have ≥ 1 severe coronary artery stenosis by invasive angiography and percutaneous coronary intervention is planned for definitive treatment or found to have ≥ 1 intermediate coronary artery stenosis and IVUS planned for lesion assessment
Coronary anatomy is deemed suitable for combined NIRS-IVUS by the interventional cardiologist performing invasive angiography and intervention
Subject is pregnant or suspected to be pregnant
Subject is unable to provide informed consent
Subject has coronary artery anatomy deemed by interventionalist as unsuitable for NIRS-IVUS