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Chemical Ice Packs for Cooling Hyperthermic Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2012 by John Lissoway, Stanford University.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
John Lissoway, Stanford University Identifier:
First received: September 24, 2012
Last updated: NA
Last verified: September 2012
History: No changes posted

A common tool to cool people in the pre-hospital setting is the chemical ice pack. These are used by athletic trainers, EMS personnel, ER staff, and people in the prehosoital setting.

The ability of these to cool a person has never been quantified, the efficiency and extent of cooling, as well as location of placement of ice packs is purely anecdotal. The purpose of this study is to determine whether strategically placed chemical ice packs will provide benefit to individuals subjected to heat stress.

Condition Intervention
Heat Stroke, Heat Exhaustion Other: Chemical Cold Pack

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Randomized Controlled Trial Assessing Effectiveness of Chemical Cold Packs Used on Various Skin Surfaces for Cooling Hyperthermic Patients

Further study details as provided by John Lissoway, Stanford University:

Primary Outcome Measures:
  • Core body temperature cooling [ Time Frame: 35 minutes ]

Estimated Enrollment: 10
Study Start Date: August 2012
Estimated Primary Completion Date: July 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Chemical Ice packs to neck, groin, axillae
Chemical ice packs will be changed out every 9 minutes
Other: Chemical Cold Pack
Experimental: Chemical Ice Packs to cheeks, palms, soles
Chemical Ice packs will be changed out every 9 minutes
Other: Chemical Cold Pack
No Intervention: no chemical ice packs


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • young healthy males > 18 years old with no active medical problems and able to run 10 km.

Exclusion Criteria:

  • Active medical problems or inability to exercise for 45 minutes in a heated room.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01694290

Contact: John B Lissoway, MD
Contact: Grant Lipman, MD

United States, California
Stanford University Recruiting
Palo Alto, California, United States
Contact: John Lissoway, MD   
Sponsors and Collaborators
Stanford University
  More Information

Responsible Party: John Lissoway, Clinical Instructor of Emergency Medicine, Stanford University Identifier: NCT01694290     History of Changes
Other Study ID Numbers: 24308
Study First Received: September 24, 2012
Last Updated: September 24, 2012

Additional relevant MeSH terms:
Heat Stroke
Heat Exhaustion
Body Temperature Changes
Signs and Symptoms
Heat Stress Disorders
Wounds and Injuries processed this record on September 21, 2017