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Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01686984
Recruitment Status : Completed
First Posted : September 18, 2012
Last Update Posted : May 14, 2015
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:

The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease.

The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.


Condition or disease Intervention/treatment
Pulmonary Gas Exchange Carbon Dioxide Other: Altered breath

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 8 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease
Study Start Date : September 2012
Primary Completion Date : May 2015
Study Completion Date : May 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Lung Diseases
U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: Altered breath
The group where the investigators alter the inspiratory and expiratory aspects of a ventilated breath.
Other: Altered breath


Outcome Measures

Primary Outcome Measures :
  1. Carbon dioxide elimination in a ventilator assisted breath. [ Time Frame: 30 minutes ]

Secondary Outcome Measures :
  1. Blood CO2 concentration. [ Time Frame: 30 minutes ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • No known primary lung disease

Exclusion Criteria:

  • Primary lung disease
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01686984


Locations
Sweden
Division of Brain, Heart and Lungs, Neurosurgical Clinic, Skane University Hospital, Lund
Lund, Skane, Sweden, 22185
Sponsors and Collaborators
Region Skane
Investigators
Principal Investigator: Mikael Bodelsson, Professor Division of Anesthesia, Skane University Hospital, Lund, Sweden
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Region Skane
ClinicalTrials.gov Identifier: NCT01686984     History of Changes
Other Study ID Numbers: 2012/381
First Posted: September 18, 2012    Key Record Dates
Last Update Posted: May 14, 2015
Last Verified: May 2015

Additional relevant MeSH terms:
Lung Diseases
Respiratory Tract Diseases