Free Fatty Acids: Short Exposure Study
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ClinicalTrials.gov Identifier: NCT01686113 |
Recruitment Status
:
Completed
First Posted
: September 17, 2012
Last Update Posted
: November 21, 2014
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Hypogeusia | Other: NEFA Other: Sucrose | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 100 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Single (Participant) |
Primary Purpose: | Basic Science |
Official Title: | Free Fatty Acids: Short Exposure Study |
Study Start Date : | May 2012 |
Actual Primary Completion Date : | May 2014 |
Actual Study Completion Date : | May 2014 |
Arm | Intervention/treatment |
---|---|
Experimental: NEFA
Participants swish and spit 5 mL of an oleic acid solution everyday for 10 days.
|
Other: NEFA
Other Name: Oleic acid
|
Active Comparator: Control
Participants swish and spit 5 mL of sucrose solution everyday for 10 days.
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Other: Sucrose |
- NEFA detection threshold [ Time Frame: 10 days ]
- Hunger [ Time Frame: 2 days ]Visual analog scale assessment of hunger level prior to testing
- BMI [ Time Frame: 1 day ]
- Taste descriptor [ Time Frame: 10 days ]Description of NEFA taste by participant, e.g., sour, bitter, etc.

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Ages Eligible for Study: | 18 Years to 55 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- good health
- available for multiple testing visits
Exclusion Criteria:
- have participated in a fat taste study in the past 6 months

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01686113
United States, Indiana | |
Purdue University | |
West Lafayette, Indiana, United States, 47907 |
Principal Investigator: | Richard D Mattes, PhD | Purdue University |
Responsible Party: | Richard Mattes, Distinguished Prof Foods and Nutrition, Purdue University |
ClinicalTrials.gov Identifier: | NCT01686113 History of Changes |
Other Study ID Numbers: |
1205012317 |
First Posted: | September 17, 2012 Key Record Dates |
Last Update Posted: | November 21, 2014 |
Last Verified: | November 2014 |
Keywords provided by Richard Mattes, Purdue University:
Taste Fat Taste Threshold Testing |
Additional relevant MeSH terms:
Ageusia Taste Disorders Sensation Disorders |
Neurologic Manifestations Nervous System Diseases Signs and Symptoms |