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Comparison of ECMO Use and Conventional Treatment in Adults With Septic Shock

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2012 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
National Taiwan University Hospital Identifier:
First received: September 11, 2012
Last updated: October 10, 2012
Last verified: September 2012
Although few cases reported successful treatment of septic shock using extracorporeal membrane oxygenation (ECMO) in adults, no studies compared ECMO to conventional treatment (without ECMO) as treatment for adults with septic shock. Since it is difficult to conduct a randomized study to allocate patients in such critical condition, we aimed to conduct a retrospective observational study using propensity score matched analysis to compare the survival of adults with septic shock treated by ECMO or conventional treatment.

Septic Shock

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Comparison of ECMO Use and Conventional Treatment in Adults With Septic Shock

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • In hospital mortality [ Time Frame: 30 days ]
    inhospital mortality as primary outcome, mean length of hospital stay around 30 days

Estimated Enrollment: 300
Study Start Date: September 2012
Estimated Study Completion Date: August 2013
Estimated Primary Completion Date: August 2013 (Final data collection date for primary outcome measure)
Conventional Group
Patients who developed refractory shock, but didn't received ECMO as salvage treatment
ECMO group
Patient who have septic shock, and progreseed to have ECMO as salvage therapy


Ages Eligible for Study:   20 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adults patient who admitted to ICU and had severe sepsis and progressed to septic shock

Inclusion Criteria:

  • age >20
  • admitted at ICU
  • septic shock

Exclusion Criteria:

  Contacts and Locations
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Please refer to this study by its identifier: NCT01685112

Contact: YuChung Chuang, MD 886-972652532

National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: YuChung Chuang, MD    886-972652532   
Principal Investigator: YuChung Chuang, MD         
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: YuChung Chuang, MD National Taiwan University Hospital
  More Information

Responsible Party: National Taiwan University Hospital Identifier: NCT01685112     History of Changes
Other Study ID Numbers: 201207079RIC
Study First Received: September 11, 2012
Last Updated: October 10, 2012

Keywords provided by National Taiwan University Hospital:

Additional relevant MeSH terms:
Shock, Septic
Pathologic Processes
Systemic Inflammatory Response Syndrome
Inflammation processed this record on April 25, 2017