Safety and Efficacy of Endotracheal Intubation Using Glidescope Video-Laryngoscope

This study has been completed.
Information provided by (Responsible Party):
Beth Israel Medical Center Identifier:
First received: September 6, 2012
Last updated: October 9, 2014
Last verified: October 2014
The safety and efficacy of a video-laryngoscope as a primary intubation tool in urgent endotracheal intubation of critically-ill patients has not been well-described in the literature. This study will answer whether using a VL will impact on the efficacy and safety of intubation compared with a traditional direct laryngoscopy.

Condition Intervention
Respiratory Failure
Procedure: Direct laryngoscopy
Device: Video laryngoscopy (Glidescope)

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Safety and Efficacy of Endotracheal Intubation by Pulmonary Critical Care Physicians in Critically-Ill Patients Using Glidescope Video-Laryngoscope

Resource links provided by NLM:

Further study details as provided by Beth Israel Medical Center:

Primary Outcome Measures:
  • First Pass Success Rate [ Time Frame: From begining of intubation to verification. Less then 5 minutes approximatly ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Severe Desaturation [ Time Frame: For 10 minutes post intubation ] [ Designated as safety issue: Yes ]
    sat <80%

  • Hypotension [ Time Frame: For 10 minutes post intubation ] [ Designated as safety issue: Yes ]

  • Cardiac Arrest [ Time Frame: For 1 hour post intubation ] [ Designated as safety issue: Yes ]
  • Complications of Intubation [ Time Frame: For 10 minutes post intubation ] [ Designated as safety issue: Yes ]
    Complications of intubation including aspiration, vomiting, esophageal intubation,and dental injury.

Enrollment: 117
Study Start Date: August 2012
Study Completion Date: April 2013
Primary Completion Date: April 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Direct laryngoscopy
Intubation will be done using direct laryngoscopy
Procedure: Direct laryngoscopy
Other Name: standard laryngoscope
Active Comparator: Video laryngoscopy
Intubation will be done using video laryngoscopy
Device: Video laryngoscopy (Glidescope)
Other Name: Glidescope Video Laryngoscope


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All patients undergoing urgent endotracheal intubation by a pulmonary critical care medicine physician

Exclusion Criteria:

  • Difficult airway
  • Oxygen saturation < 92% despite adequate mask ventilation
  Contacts and Locations
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Please refer to this study by its identifier: NCT01683526

United States, New York
Beth Isreal Medical Center
New York, New York, United States, 10003
Sponsors and Collaborators
Beth Israel Medical Center
Principal Investigator: Michael Silverberg, MD Beth Israel Medical Center
  More Information

Responsible Party: Beth Israel Medical Center Identifier: NCT01683526     History of Changes
Other Study ID Numbers: 139-12 
Study First Received: September 6, 2012
Results First Received: May 23, 2014
Last Updated: October 9, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by Beth Israel Medical Center:
Urgent endotrachel intubation
Direct laryngoscopy
Video laryngoscopy
Critical Care

Additional relevant MeSH terms:
Respiratory Insufficiency
Respiration Disorders
Respiratory Tract Diseases processed this record on May 23, 2016