Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2012 by Shandong University.
Recruitment status was  Recruiting
Information provided by (Responsible Party):
Ming Hou, Shandong University Identifier:
First received: September 3, 2012
Last updated: NA
Last verified: September 2012
History: No changes posted
This study is designed to collect bone marrow and/or peripheral blood cells and plasma, for the analysis of adhesion molecules, chemokines and their receptors from newly-diagnosed aplastic anemia patients, and patients treated with antithymocyte globulin plus cyclosporine

Aplastic Anemia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Shandong University:

Primary Outcome Measures:
  • hematologic response [ Time Frame: 6 months following antithymocyte globulin plus cyclosporine treatment ] [ Designated as safety issue: No ]
    hematologic response at 6 months following antithymocyte globulin plus cyclosporine treatment, defined as no longer meeting the criteria for severe aplastic anemia

Estimated Enrollment: 70
Study Start Date: February 2009
Estimated Study Completion Date: November 2012
Acquired Aplastic Anemia Patients Treated with Antithymocyte Globulin plus Cyclosporine


Ages Eligible for Study:   16 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients With Aplastic Anemia

Inclusion Criteria:

  • patients who fulfilled entry criteria of acquired aplastic anemia age range 16-70 years

Exclusion Criteria:

  • Patients complicated with diabetes, tumor, pregnancy, active infection, or connective tissue diseases, such as systemic lupus erythematosus.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01680055

China, Shandong
Qilu Hospital, Shandong University Recruiting
Jinan, Shandong, China, 250012
Contact: Jun Peng, MD    13553157577   
Principal Investigator: Ming Hou, MD         
Sponsors and Collaborators
Shandong University
  More Information

No publications provided

Responsible Party: Ming Hou, Director, Shandong University Identifier: NCT01680055     History of Changes
Other Study ID Numbers: Aplastic Anemia 1
Study First Received: September 3, 2012
Last Updated: September 3, 2012
Health Authority: China: National Natural Science Foundation

Additional relevant MeSH terms:
Anemia, Aplastic
Bone Marrow Diseases
Hematologic Diseases processed this record on November 27, 2015