Surgical Prep in Hand Surgery

This study has been completed.
Information provided by (Responsible Party):
John Fowler, University of Pittsburgh Identifier:
First received: August 23, 2012
Last updated: June 2, 2015
Last verified: June 2015
The purposes of this study are to identify the common bacterial flora on the hand and evaluate the efficacy of readily available skin-preparation solutions in the elimination of bacterial pathogens from the surgical site following skin preparation. The null hypothesis is that there is no difference in the efficacy of Chloraprep, Duraprep, and betadine in pre-operative skin preparation in clean, elective hand surgery cases.

Condition Intervention
Surgical Scrubbing
Other: Skin culture

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Efficacy of Surgical Preparation Solutions in Hand Surgery

Further study details as provided by University of Pittsburgh:

Primary Outcome Measures:
  • Number of positive cultures [ Time Frame: after skin prep solution has dried ] [ Designated as safety issue: No ]

Enrollment: 240
Study Start Date: December 2012
Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Chloraprep Other: Skin culture
Culture swab used to culture skin adjacent to incision
Duraprep Other: Skin culture
Culture swab used to culture skin adjacent to incision
Betadine only Other: Skin culture
Culture swab used to culture skin adjacent to incision


Ages Eligible for Study:   18 Years to 89 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
All patients undergoing clean, elective hand surgery without implants

Inclusion Criteria:

  • the following procedures (carpal tunnel release, trigger finger release, cyst excision, 1st dorsal compartment release)

Exclusion Criteria:

  • prisoners
  • pregnant women
  Contacts and Locations
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Please refer to this study by its identifier: NCT01676051

United States, Pennsylvania
Montefiore Hospital
Pittsburgh, Pennsylvania, United States, 15213
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
Principal Investigator: John Fowler, MD University of Pittsburgh