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Social Network Interventions in Rural Honduras

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ClinicalTrials.gov Identifier: NCT01672580
Recruitment Status : Completed
First Posted : August 27, 2012
Last Update Posted : March 19, 2015
Sponsor:
Collaborator:
Yale University
Information provided by (Responsible Party):
Thomas Keegan, Ph.D., Yale University

Brief Summary:

This project will examine the spread of health interventions with a randomized control trial design by introducing public health interventions in 32 villages in the Honduran Department of Lempira. Based on identified public health needs in the region, namely improved drinking water and diet, this study will provide training on the use of chlorine (sodium hypochlorite) for water purification and multivitamins for nutritional supplementation. In some villages, individuals selected for their social connectedness will be trained and given coupons that can be redeemed for either chlorine bleach or multivitamins, and these persons will be asked to spread this information and distribute coupons to four people of their choosing. In other villages, individuals selected at random will receive the same training, materials, and instructions. A second wave of coupon distribution will provide coupons to those who received a coupon from the original "seed" groups so that they may disperse these coupons further out in the social networks. Over the following months, study investigators will look at how knowledge of these health practices, and uptake or and adherence to the practices, spreads throughout the villages.

More specifically, the investigators will examine the speed and extent of spreading of these new health practices after introducing them to three different initial "seed" groups: (1) people chosen on the basis of being named as a friend by many people in their village, (2) people chosen based on being named as a friend by a randomly chosen individual, and (3) a group of randomly chosen individuals. It is hypothesized that spread will occur faster and/or to a greater extent when the intervention is started in groups 1 and 2 versus group 3 (control group).


Condition or disease Intervention/treatment Phase
Malnutrition Dysentery Social Transmission of Health Behaviors Behavioral: exposure to vitamin use Behavioral: exposure to water chlorination Behavioral: high in-degree Behavioral: nominated by random Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 5773 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single (Participant)
Primary Purpose: Basic Science
Official Title: Diffusion of Health Interventions Across Social Networks in Honduran Villages
Study Start Date : August 2012
Actual Primary Completion Date : October 2013
Actual Study Completion Date : October 2014

Arm Intervention/treatment
Active Comparator: Random-Cloro
exposure to water chlorination
Behavioral: exposure to water chlorination
"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village
Other Name: Clorox
Active Comparator: Random-Vitamin
exposure to vitamin use
Behavioral: exposure to vitamin use
"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village
Other Name: Medox Forte
Experimental: Indegree-Cloro
high in-degree, exposure to water chlorination
Behavioral: exposure to water chlorination
"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village
Other Name: Clorox
Behavioral: high in-degree
"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree
Experimental: Indegree-Vitamin
high in-degree, exposure to vitamin use
Behavioral: exposure to vitamin use
"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village
Other Name: Medox Forte
Behavioral: high in-degree
"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree
Experimental: Nominated-Cloro
nominated by random, exposure to water chlorination
Behavioral: exposure to water chlorination
"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village
Other Name: Clorox
Behavioral: nominated by random
"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual
Experimental: Nominated-Vitamin
nominated by random, exposure to vitamin use
Behavioral: exposure to vitamin use
"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village
Other Name: Medox Forte
Behavioral: nominated by random
"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual



Primary Outcome Measures :
  1. Intervention Spread [ Time Frame: October 2012 ]
    Use of health product among community members will be tracked.



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Ages Eligible for Study:   15 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Residents of Targeted Communities, ages 15 and up

Exclusion Criteria:

  • Children younger than age 15

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01672580


Locations
United States, Connecticut
Yale University
New Haven, Connecticut, United States, 06517
Sponsors and Collaborators
Harvard University
Yale University
Investigators
Principal Investigator: Nicholas A Christakis, MD, PhD Yale University
Study Director: Thomas Keegan, PhD Yale University

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Thomas Keegan, Ph.D., Project Director, Yale University
ClinicalTrials.gov Identifier: NCT01672580     History of Changes
Other Study ID Numbers: Lempira_Phase2
First Posted: August 27, 2012    Key Record Dates
Last Update Posted: March 19, 2015
Last Verified: March 2015

Keywords provided by Thomas Keegan, Ph.D., Yale University:
social networks
nutrition
vitamins
chlorine

Additional relevant MeSH terms:
Malnutrition
Dysentery
Nutrition Disorders
Gastroenteritis
Gastrointestinal Diseases
Digestive System Diseases
Intestinal Diseases
Vitamins
Micronutrients
Growth Substances
Physiological Effects of Drugs