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The Diastolic Pressure Gradient for Patients With Acute Coronary Syndrome: Evaluation of Non Culprit Lesions (FORECAST)

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ClinicalTrials.gov Identifier: NCT01671631
Recruitment Status : Unknown
Verified August 2012 by Ciro Indolfi, University Magna Graecia.
Recruitment status was:  Recruiting
First Posted : August 23, 2012
Last Update Posted : August 23, 2012
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:

The assessment of non-culprit stenoses is an important issue in ACS. Adenosine administration is currently required for functional evaluation of stenosis severity using the fractional flow reserve (FFR). An alternative adenosine-independent index of coronary stenosis, the instantaneous wave-free ratio (iFR), was recently introduced.

Aim of the present study will be to evaluate the trans-stenotic instantaneous wave-free pressure gradient (iFG), the instantaneous wave-free ratio (iFR) and the fractional flow reserve (FFR) in ACS patients.


Condition or disease Intervention/treatment
Functional Evaluation of Non Culprit Lesions in ACS Patients Other: Measurement of intracoronary pressure

Study Design

Study Type : Observational
Observational Model: Cohort
Time Perspective: Prospective
Groups and Cohorts

Group/Cohort Intervention/treatment
Acute Coronary Syndrome
Patients with Acute Coronary Syndrome and multivessel coronary artery disease undergoing functional evaluation of non-culprit lesions.
Other: Measurement of intracoronary pressure


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with Acute Coronary Syndrome and multivessel coronary artery disease.
Criteria

Inclusion Criteria:

  • age 40 to 80 years
  • recent Acute Coronary Syndrome
  • indication for coronary angiography
  • presence of at least one non-culprit lesion requiring functional evaluation with fractional flow reserve (FFR):

Exclusion Criteria:

  • Haemodynamically significant valvular disease
  • controindication for Adenosin administration
  • previous CABG on the index vessel
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01671631


Contacts
Contact: Ciro Indolfi, Prof +3909613647067 clinicaltrials-cardioumg@email.it

Locations
Italy
Cardiologia Interventistica UMG Recruiting
Catanzaro, Calabria, Italy, 88100
Contact: Ciro Indolfi, Prof.    +3909613647067    clinicaltrials-cardioumg@email.it   
Principal Investigator: Ciro Indolfi, MD         
Sponsors and Collaborators
University Magna Graecia
More Information

Additional Information:
Responsible Party: Ciro Indolfi, Professor, University Magna Graecia
ClinicalTrials.gov Identifier: NCT01671631     History of Changes
Other Study ID Numbers: FORECAST
First Posted: August 23, 2012    Key Record Dates
Last Update Posted: August 23, 2012
Last Verified: August 2012