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Impact of Follicular and Blood G-CSF on Pregnancy and Implantation Rate During Modified Natural in Vitro Fertility Cycle (G-CSF FIVnat)

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ClinicalTrials.gov Identifier: NCT01668225
Recruitment Status : Recruiting
First Posted : August 20, 2012
Last Update Posted : July 25, 2017
Sponsor:
Information provided by (Responsible Party):
OVO R & D

Brief Summary:
Recently, scientists look into G-CSF (Granulocyte - Colony Stimulatin Factor). The use of this molecule is increasing in reproduction pathology. High level of follicular and blood G-CSF on the day of oocyte retrieval could correlate with higher pregnancy and implantation rates.

Condition or disease Intervention/treatment
Infertility Procedure: Blood test

Study Type : Observational
Estimated Enrollment : 224 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Impact of Follicular and Blood G-CSF on Pregnangcy and Implantation Rate During Modified Natural in Vitro Fertility Cycle
Study Start Date : March 2012
Estimated Primary Completion Date : January 2020
Estimated Study Completion Date : January 2020

Group/Cohort Intervention/treatment
G-CSF FIV nat
Patient following a natural In Vitro Fecondation cycle
Procedure: Blood test

Taking blood sample of the patient during the day 3, triggering day, oocyte collection day and pregnancy test day.

Taking the follicular fluid during the oocyte collection day




Primary Outcome Measures :
  1. Serum and / or follicular minimum level of G-CSF predictive of pregnancy [ Time Frame: 6 months ]

Biospecimen Retention:   Samples Without DNA
Serum sample Follicular fluid


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Ages Eligible for Study:   18 Years to 43 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Women with a natural cycle of an In Vitro Fecondation
Criteria

Inclusion Criteria:

  • Women between 18 and 43 years old
  • Women natural In Vitro Fecondation

Exclusion Criteria:

  • No exclusion criteria

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01668225


Contacts
Contact: Cynthia Levesque (514) 798-2000 ext 755 c.levesque@cliniqueovo.com
Contact: Michael Harnois (514) 798-2000 ext 755 m.harnois@cliniqueovo.com

Locations
Canada, Quebec
Ovo Fertilité Recruiting
Montréal, Quebec, Canada, J4P 2S4
Contact: Shirley Brugerie, Director    (514) 798-2000 ext 753    s.brugerie@cliniqueovo.com   
Contact: Cynthia Levesque, Research assistant    514-798-2000 ext 755    c.levesque@cliniqueovo.com   
Sponsors and Collaborators
OVO R & D
Investigators
Principal Investigator: Pierre Lehmann, MD Clinique ovo

Responsible Party: OVO R & D
ClinicalTrials.gov Identifier: NCT01668225     History of Changes
Other Study ID Numbers: OVO-11-02
First Posted: August 20, 2012    Key Record Dates
Last Update Posted: July 25, 2017
Last Verified: July 2017

Additional relevant MeSH terms:
Infertility
Genital Diseases, Male
Genital Diseases, Female