Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01663597|
Recruitment Status : Completed
First Posted : August 13, 2012
Last Update Posted : August 29, 2013
Aberrations play a significant role in the visual process and can be divided in lower-order and higher-order aberrations. The former can be measured using the commercially available IOL Master (Carl Zeiss Meditec AG, Germany) and have profound influence on visual acuity. Higher-order aberrations do not significantly influence visual acuity but affect the quality of vision and can cause halos, double vision, and night vision disturbances.
Background Cataract surgery has become a routine procedure in the developed countries. During this surgery, a foldable intraocular lens is usually inserted into the capsular bag. However, these lenses do not account for individual optical biometry data or aberrations. Therefore, it is important to provide data for ametropic and emmetropic eyes as this information might improve future intraocular lens design and lead to individually adapted lenses for yielding optimal visual acuity and quality results.
The aim of the present study is to clarify the correlation between refractive errors/axial eye length and spherical aberrations of the cornea.
|Condition or disease|
|Refractive Errors Axial Length, Eye Corneal Wavefront Aberration|
|Study Type :||Observational|
|Actual Enrollment :||160 participants|
|Official Title:||Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes|
|Study Start Date :||August 2012|
|Primary Completion Date :||May 2013|
|Study Completion Date :||May 2013|
40 subjects with high grarde myopia ranging from -10 diopters to -4.01 diopters
40 subjects with moderate myopia ranging from -4 diopters to -1.01 diopter
40 subjects with emmetropia, -1 diopter to +1 diopter
40 subjects with hyperopia, +1.01 diopter and more
- Axial eye length [ Time Frame: 1 day ]
- Refractive error [ Time Frame: 1 day ]
- Corneal radius [ Time Frame: 1 day ]
- Pupil diameter [ Time Frame: 1 day ]
- Anterior chamber depth [ Time Frame: 1 day ]
- Anterior corneal topography [ Time Frame: 1 day ]
- Corneal thickness map [ Time Frame: 1 day ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01663597
|Department of Clinical Pharmacology, Medical University of Vienna|
|Vienna, Austria, 1090|