Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer
The purpose of this study is to find out whether Endoscopic Ultrasound (EUS) can detect early stage pre-cancerous or cancerous changes in the pancreas in patients at high-risk for the development of pancreatic cancer. Endoscopic refers to the use of an instrument called an endoscope - a thin, flexible tube with a tiny video camera and light on the end. Ultrasound refers to an imaging technique that uses sound waves to produce pictures. EUS in this research study is a method of combining endoscopy and ultrasound imaging to obtain high quality images of the pancreas.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer at Moffitt Cancer Center and Lehigh Valley Hospital|
- Number of Abnormalities Detected by EUS [ Time Frame: Average of 5 years ] [ Designated as safety issue: No ]To determine whether targeted screening of these high-risk individuals using Endoscopic Ultrasound (EUS) at regular intervals can detect precancerous pancreas changes or early stage asymptomatic pancreatic cancer.
|Study Start Date:||June 2007|
|Estimated Study Completion Date:||September 2017|
|Estimated Primary Completion Date:||September 2017 (Final data collection date for primary outcome measure)|
Endoscopic Ultrasound (EUS) Participants
High-risk for Pancreatic Cancer: Patients with 2 or more relatives with pancreatic cancer and a first degree relationship with at least one of the relatives with pancreatic cancer.
Procedure: Endoscopic Ultrasound (EUS)
Ultrasound scope will be passed through the participant's mouth into their stomach and their pancreas will be evaluated completely by the ultrasound scope. If an abnormality is found in their pancreas, a biopsy may be performed to obtain a diagnosis.
Other Name: ultrasound scope
Please refer to this study by its ClinicalTrials.gov identifier: NCT01662609
|United States, Florida|
|H. Lee Moffitt Cancer Center and Research Institute||Recruiting|
|Tampa, Florida, United States, 33612|
|Contact: Marjorie Brelsford 813-745-6704 firstname.lastname@example.org|
|Principal Investigator: Jason Klapman, M.D.|
|Sub-Investigator: Barbara Centeno, M.D.|
|Sub-Investigator: Pamela Hodul, M.D.|
|Sub-Investigator: Mokenge Malafa, M.D.|
|Sub-Investigator: Thomas Sellers, Ph.D.|
|Sub-Investigator: Catherine Phelan, M.D., Ph.D.|
|United States, Pennsylvania|
|Lehigh Valley Health Network||Recruiting|
|Allentown, Pennsylvania, United States, 18105|
|Contact: Pam Smith 813-745-6993 email@example.com|
|Principal Investigator: Rohit Sharma, M.D.|
|Sub-Investigator: Hiral Shah, M.D.|
|Sub-Investigator: Shashin Shah, M.D.|
|Principal Investigator:||Jason Klapman, M.D.||H. Lee Moffitt Cancer Center and Research Institute|